Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1997-12-29
2000-06-20
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424 45, 424499, 424502, 514938, 514958, 514251, 264 5, 264 7, 264 12, 264 13, A61K 914, A61K 972
Patent
active
060775432
ABSTRACT:
Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions of the components and spray drying them simultaneously in a spray dryer. The hydrophilic and hydrophobic component are separately dissolved in separate solvents and directed simultaneously through a nozzle, usually a coaxial nozzle, into the spray dryer. The method provides dry powders having relatively uniform characteristics.
REFERENCES:
patent: 4486435 (1984-12-01), Schmidt et al.
patent: 4540602 (1985-09-01), Motoyama et al.
patent: 4590206 (1986-05-01), Forrester et al.
patent: 4670419 (1987-06-01), Uda et al.
patent: 4898781 (1990-02-01), Onouchi et al.
patent: 4999189 (1991-03-01), Kogan et al.
patent: 5000888 (1991-03-01), Kilbride, Jr. et al.
patent: 5026550 (1991-06-01), Aeschbach et al.
patent: 5260306 (1993-11-01), Boardman et al.
patent: 5376386 (1994-12-01), Ganderton et al.
patent: 5510118 (1996-04-01), Bosch et al.
patent: 5518187 (1996-05-01), Bruno et al.
patent: 5534270 (1996-07-01), De Castro
Bloch et al., "Dispersions of hydrochlorothiazide and chlorthalidone in pentaerythritol" Pharm. Acta Helv. (1983) 58(1):14-22. An English abstract is also enclosed herewith.
Dialog.RTM. Abstract of German Patent Publication No. DE 2209477. One page total.
Dialog.RTM. Abstract of French Patent Publication No. FR. 2594693 One page total.
Dialog.RTM. Abstract of Japanese Patent Publication No. JP 4036233. One page total.
Dialog.RTM. Abstract of Japanese Patent Publication No. JP 7101881. One page total.
Dialog.RTM. Abstract of Japanese Patent Publication No. JP 7101883. One page total.
Dialog.RTM. Abstract of Japanese Patent Publication No. JP 7101884. One page total.
Dialog.RTM. Abstract of Japanese Patent Publication No. JP 7101882. One page total.
Dialog.RTM. Abstract of Japanese Patent Publication No. JP 7242568. One page total.
Dialog.RTM. Abstract of Japanese Patent Publication No. JP 8067666. One page total.
Mumenthaler et al. "Feasibility study on spray-drying protein pharmaceuticals: Recombinant human growth hormone and tissue-type plasminogen activator" Pharm. Res. (1994) 11(1):12-20.
Brewer Thomas K.
Clark Andrew
Gordon Marc S.
Channavajjala Lakshmi
Inhale Therapeutic Systems
Page Thurman K.
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