Chemistry: molecular biology and microbiology – Apparatus – Differentiated tissue perfusion or preservation apparatus
Reexamination Certificate
2008-01-24
2011-10-11
Bowers, Nathan (Department: 1775)
Chemistry: molecular biology and microbiology
Apparatus
Differentiated tissue perfusion or preservation apparatus
C435S289100, C435S293100, C435S304100, C435S305100, C435S001100, C435S001200, C435S285100, C435S299100, C435S297200, C600S036000, C623S915000, C623S916000, C623S921000
Reexamination Certificate
active
08034608
ABSTRACT:
Hybrid synthetic grafts and embodiments of systems and methods for producing hybrid vascular grafts that can yield implantable grafts that combine synthetic grafts with living cells. Embodiments of systems can include a pressure/flow loop subsystem having an external flow loop system coupled to a specimen holder, where the pressure/flow loop subsystem is capable of adjusting at least two dynamic conditions in the specimen holder or a diameter of a specimen in the specimen holder. Embodiments of methods can promote endothelialization of a hybrid hemodialysis access graft or a hybrid femoral artery bypass graft by placing the hybrid hemodialysis access graft or the hybrid femoral artery bypass graft in a system embodiment according to the invention under conditions effective to promote stem cells to form a confluent monolayer on the hybrid graft.
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patent: 6174719 (2001-01-01), Elizondo et al.
patent: 6416995 (2002-07-01), Wolfinbarger
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Bowers Nathan
ICE Development Technologies, LLC
Vasquez, Esq. Rene A.
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