Systems and methods for the analysis of protein phosphorylation

Details Systems and methods for the analysis of protein phosphorylation Systems and methods for the analysis of protein phosphorylation

2006-04-11

2006-04-11

Weber, Jon (Department: 1653)

Chemistry: analytical and immunological testing

Nuclear magnetic resonance, electron spin resonance or other...

C436S056000, C436S086000, C530S352000, C530S340000, C530S345000, C530S407000, C530S355000, C530S343000, C530S811000

Reexamination Certificate

active

07026167

ABSTRACT:
The present invention relates to a method of applying mass spectrometry to analyzing peptides or proteins, especially in the proteome setting. More particularly, the invention relates to a mass spectrometry-based method for detection of protein/peptide phosphorylation wherein the side chains of glutamic acid and/or aspartic acid residues of said peptides or proteins are chemically modified as to improve the selectivity/efficiency of identification of the phosphorylated protein/peptide.

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