Systems and methods for measuring fluid properties

Chemistry: analytical and immunological testing – Clotting or clotting factor level tests

Reexamination Certificate

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C436S052000, C436S063000, C436S164000, C436S165000, C422S073000, C422S081000, C422S082050, C422S082090, C435S002000

Reexamination Certificate

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10431358

ABSTRACT:
A method for measuring properties of a fluid including placing a quantity of fluid in a container; inducing flow in the fluid wherein the flow is substantially streamlined in at least a measuring region of the container, and wherein the fluid is recirculated through the measuring region; creating a mixing region separate from the measuring region sufficient to substantially mix the fluid; and measuring a property of the fluid in the streamlined region. The invention is of particular interest in the assessment of blood platelet function. The method provides specific localized regions of thorough mixing that enable reproducible platelet aggregation, and also provides specific localized regions of streamlined flow that enable certain modalities of assessing aggregation. Both of these regions of flow are induced such that damage to platelet aggregates and other blood components is minimized.

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