Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...
Patent
1996-06-26
1998-08-11
Rimell, Sam
Surgery
Means for introducing or removing material from body for...
Treating material introduced into or removed from body...
604164, 6048901, A61M 5178
Patent
active
057921105
ABSTRACT:
Systems for delivering a therapeutic agent to a selected site in a subject are disclosed. These systems enable precise placement of selected amounts, e.g., very small amounts, of a therapeutic agent to a predetermined site or sites in a three dimensional array in a subject with minimal trauma to the subject. These delivery systems include a guide cannula for penetrating a selected site in a subject to a predetermined depth and a delivery cannula for delivering the therapeutic agent to the subject. The guide cannula has an axial bore extending therethrough with an open proximal end and an opening at a distal portion thereof. The delivery cannula has an axial bore extending therethrough, a flexible distal end portion, and an outer diameter which is less than the inner diameter of the guide cannula. Methods of delivering therapeutic agents to selected sites in a subject using these delivery systems are also described.
REFERENCES:
patent: 4243050 (1981-01-01), Littleford
patent: 4518383 (1985-05-01), Evans
patent: 4578061 (1986-03-01), Lemelson
patent: 4581019 (1986-04-01), Curelaru et al.
patent: 4769005 (1988-09-01), Ginsburg et al.
patent: 4846799 (1989-07-01), Tanaka et al.
patent: 5004457 (1991-04-01), Wyatt et al.
patent: 5006122 (1991-04-01), Wyatt et al.
patent: 5106627 (1992-04-01), Aebischer et al.
patent: 5156844 (1992-10-01), Aebischer et al.
patent: 5182111 (1993-01-01), Aebischer et al.
patent: 5306239 (1994-04-01), Gurmarnik et al.
patent: 5480389 (1996-01-01), McWha et al.
patent: 5487739 (1996-01-01), Aebischer et al.
patent: 5554148 (1996-09-01), Aebischer et al.
Freeman, T. et al., "Bilateral Fetal Nigral Transplantation into the Postcommissural Putamen in Parkinson's Disease," Annals of Neurology, vol. 38, No. 3, 379-388 (1995).
Kordower, J. et al., "Neuropathological Evidence of Graft Survival and Striatal Reinnervation After the Transplantation of Fetal Mesencephalic Tissue in a Patient with Parkinson's Disease," The New England Journal of Medicine, vol. 332, No. 17, 1118-1124 (1995).
Widner, H. et al., "Bilateral Fetal Mesencephalic Gafting in Two Patients with Parkinsonism Induced by 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)," The New England Journal of Medicine, vol. 327, No. 22, 1556-1563 (1992).
Brecknell, J.E. and Fawcett, J.W. (Jan. 1996) Exp. Neurol. 138:338-343.
Racunas Robert V.
Rimell Sam
Silveri Jean M.
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