Systems and methods for characterizing kidney diseases

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

Reexamination Certificate

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Reexamination Certificate

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07138229

ABSTRACT:
The present invention relates to methods of diagnosing, predicting and monitoring kidney diseases, including acute renal failure, renal tubular interstitial disease and glomerulonephritis. In particular, the present invention relates to the detection, prediction and monitoring of kidney diseases by detection of CXCR3 and CCL chemokines in urine. The present invention further relates to methods and compositions for assessing the efficacy of agents and interventions used to treat kidney diseases.

REFERENCES:
Romagnani et al, J. Am. Soc. Nephrology, vol. 10, pp. 2518-2526, (1999).
Loetscher et al, J. Exp. Med., vol. 184, pp. 963-969, (Sep. 1996).

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