Systems and methods for calibrating osmolarity measuring...

Details Systems and methods for calibrating osmolarity measuring... Systems and methods for calibrating osmolarity measuring...

2007-04-17

2007-04-17

Williams, Hezron (Department: 2856)

Measuring and testing

Instrument proving or calibrating

Gas or liquid analyzer

C073S001020

Reexamination Certificate

active

11327884

ABSTRACT:
An osmolarity measuring system comprising microscale electrode arrays is configured to account for variations and defects in the arrays using a tiered approach comprising several calibration methods. One method accounts for the intrinsic conductivity of the electrodes and subtracts out the intrinsic conductivity on a pair-wise basis, when determining osmolarity of a sample fluid. Other methods in the tiered approach use standards to determine calibration factors for the electrodes that can then be used to adjust subsequent osmolarity measurements for a sample fluid. The use of a standard can also be combined with a washing step.

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International Search Report for PCT/US05/01576 dated Mar. 6, 2006.

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