Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2005-09-15
2009-10-27
Myers, Carla (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007100, C435S091200, C536S023500, C536S024310
Reexamination Certificate
active
07608395
ABSTRACT:
The present invention provides compositions and methods for aiding in the diagnosis, monitoring and prognosis of SLE in a subject and for identifying potential therapeutic agents to treat and/or ameliorate the symptoms associated with SLE. Accordingly, embodiments of the invention are directed to methods of identifying the gene expression profile of a suitable sample by screening for the presence of a differentially expressed SLE-associated gene isolated from a sample containing or suspected of containing a cell that can differentially express an SLE-associated gene.
REFERENCES:
patent: 3817837 (1974-06-01), Rubenstein et al.
patent: 3850752 (1974-11-01), Schuurs et al.
patent: 3939350 (1976-02-01), Kronick et al.
patent: 3996345 (1976-12-01), Ullman et al.
patent: 4227437 (1980-10-01), Inloes et al.
patent: 4275149 (1981-06-01), Litman et al.
patent: 4366241 (1982-12-01), Tom et al.
patent: 4603102 (1986-07-01), Himmelmann et al.
patent: 4682195 (1987-07-01), Yilmaz
patent: 4683202 (1987-07-01), Mullis
patent: 4695188 (1987-09-01), Pulkkinen
patent: 5310952 (1994-05-01), Heveling
patent: 5322770 (1994-06-01), Gelfand
patent: 5399491 (1995-03-01), Kacian et al.
patent: 5405783 (1995-04-01), Pirrung et al.
patent: 5412087 (1995-05-01), McGall et al.
patent: 5427202 (1995-06-01), Behring et al.
patent: 5445934 (1995-08-01), Fodor et al.
patent: 5578832 (1996-11-01), Trulson et al.
patent: 5631734 (1997-05-01), Stern et al.
patent: 5795716 (1998-08-01), Chee et al.
patent: 6040138 (2000-03-01), Lockhart et al.
patent: 6391550 (2002-05-01), Lockhart et al.
patent: 6596501 (2003-07-01), Roth
patent: 2003/0148298 (2003-08-01), O'Toole et al.
patent: 2004/0033498 (2004-02-01), Behrens et al.
patent: 2004/0241726 (2004-12-01), Liew et al.
patent: 0 320 308 (1989-06-01), None
patent: 95/20681 (1995-08-01), None
patent: 97/10365 (1997-03-01), None
patent: 03/016476 (2003-02-01), None
Liu et al . Clinical Immunology. 2004. 112: 225-230.
Coleman, R.A. Drug Discovery Today. 2003. 8: 233-235.
GeneCard Database for DNAPTP6/LOC2601, available via URL <genecards.org/cgi-bin/carddisp.pl?gene=LOC26010>.
GeneCard Database for DNAPTP6/LOC2601, available via URL <genecards.org/cgi-bin/carddisp.pl?gene=PAFAH1B>.
GeneCard Database for DNAPTP6/LOC2601, available via URL <genecards.org/cgi-bin/carddisp.pl?gene=TDRD7>.
GeneCard Database for DNAPTP6/LOC2601, available via URL <genecards.org/cgi-bin/carddisp.pl?gene=GPR84>.
GeneCard Database for DNAPTP6/LOC2601, available via URL <genecards.org/cgi-bin/carddisp.pl?gene=GTPBP2>.
GeneCard Database for DNAPTP6/LOC2601φ available via URL <genecards.org/cgi-bin/carddisp.pl?gene=B4GALT5>.
GeneCard Database for DNAPTP6/LOC2601, available via URL <genecards.org/cgi-bin/carddisp.pl?gene=FRAT2>.
International Search Report and Written Opinion for PCT/US2006/036320 dated Aug. 20, 2007.
National Center for Biotechnology Information. National Library of Medicine, NIH (Bethesda, MD, USA). GenBank Accession No. AW292752, Jan. 16, 2000.
Affymetrix, GeneChip Human Genome U1333 Arrays. 2003.
Arce et al., “Increased Frequency of Pre-germinal Center B Cells and Plasma Cell Precursors in the Blood of Children with Systemic Lupus Erythematosus,” J Immunol (2001), 167:2361-2369.
Bennett, et al., “Interferon and Granulopoiesis Signatures in Systemic Lupus Erythematosus Blood,” J. Exp. Med. (2003), 197:711-723.
Baechler, et al., “Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus,” Proc. Natl. Acad. Sci. USA (2003), 100:2610-2615.
Hardin, J.A., “Directing Autoimmunity to Nucleoprotein Particles: The Impact of Dendritic Cells and Interferon α in Lupus,” J. Exp. Med. (2003), 185:1101-1111.
Tibshirani et al., “Diagnosis of multiple cancer types by shrunken centroids of gene expression.” Proc. Natl. Acad. Sci. USA (2002), 99:6567-6572.
Supplementary European Search Report for EP 06814874.1 dated May 4, 2009.
Alcorta, D., et al., “Microarray Studies of Gene Expression in Circulating Leukocytes in Kidney Disease,” Exp Nephrol (2002), 10:139-149.
Franchin, G., et al., “Pathogenesis of SLE: implications for rational therapy,” Drug Discovery Today: Disease Mechanisms (2004), 1:303-308.
Pereira, E., et al., “Immunosuppressive therapy modulates T lymphocyte gene expression in patients with systemic lupus erythematosus,” Immunology (2004), 113:99-105.
Banchereau Jacques F.
Bennett Lynda B.
Pascual Maria Virginia
Baylor Research Institute
Chalker Flores LLP
Flores Edwin S.
Myers Carla
Singleton Chainey P.
LandOfFree
Systemic lupus erythematosus diagnostic assay does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Systemic lupus erythematosus diagnostic assay, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Systemic lupus erythematosus diagnostic assay will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4139852