Systemic control of parasites

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514521, 514298, 514667, 514594, 514354, 514245, 514369, 514241, 514219, 514450, 514712, 514452, 501123, 549264, 424405, 568363, 568592, A01N 4382

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active

057287198

ABSTRACT:
The present invention is a method for controlling ectoparasites. More particularly, the invention relates to a method of treatment in which the warm blooded animal is dosed with an ovicidally effective amount of a heterocyclic nitrogen compound selected from the group represented by the formula: ##STR1## wherein R.sub.1, is either one of the following groups: ##STR2## in which R.sub.7, R.sub.8, R.sub.9, R.sub.10, R.sub.11, R.sub.12, R.sub.13, R.sub.14, R.sub.15, R.sub.16, and R.sub.17 are, the same or different, each a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 alkoxy group, a C.sub.1 -C.sub.4 alkylthio group, a trifluoro methyl group or a vitro group, R.sub.18, R.sub.19, R.sub.20 and R.sub.21 are, the same or different, each a hydrogen atom or a methyl group, k is an integer of 0 to 1 and 1 is an integer of 0 to 3; R.sub.2 and R.sub.3 are, the same or different, each a hydrogen atom, a halogen atom or a methyl group; R.sub.4 is a halogen atom or a methyl group; R.sub.5 and R.sub.6 are, the same or different, each a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 haloalkyl group or a C.sub.1 -C.sub.4 haloalkoxy group; X, Y and Z are, the same or different, each an oxygen atom, a sulfur atom or a methylene group, m is an integer of 0 to 4, and n is an integer of 0 to 2, which is transmitted to the ectoparasite by the animal's blood. In a further embodiment, a compound selected from the group consisting of ivermectin, milbemycin, milbemycin oxime, moxidectin and avermectin and avermectin derivatives.

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