Surgery – Respiratory method or device – Ozone or ion generation
Patent
1978-10-23
1980-08-19
Rosenbaum, C. Fred
Surgery
Respiratory method or device
Ozone or ion generation
A61M 3100
Patent
active
042178983
ABSTRACT:
A system is disclosed for delivering an active agent to a fluid environment of use. The system comprises a microporous reservoir, an active agent housed in the reservoir, a surface that defines an exposed area of the reservoir for releasing agent from the reservoir to the environment, and a wall impermeable to both fluid and agent that surrounds the remaining, unexposed surfaces of the reservoir. In operation, when the system is in the environment with the exposed surface presented to fluid, fluid enters the system through the exposed surface causing agent to diffuse from within the system, which agent is released from the exposed surface of the system to the environment at a controlled rate over time.
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patent: 2928770 (1960-03-01), Bardani
patent: 2987445 (1961-06-01), Levesque
patent: 3146169 (1965-05-01), Stephenson
patent: 3538214 (1970-11-01), Polli et al.
patent: 3938515 (1976-02-01), Leeper et al.
patent: 3948254 (1976-04-01), Zaffaroni
patent: 3977404 (1976-08-01), Theeuwes
Acta Pharm. Suecia, vol. 8, pp. 153-168, 1971, Sjorgen.
J. Pharm. Sci., vol. 60, pp. 1028-1033, 1971, Arcy et al.
ALZA Corporation
Ciotti Thomas E.
Mandell Edward L.
Rosenbaum C. Fred
Sabatine Paul L.
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