System reconstruction: integrative analysis of biological data

Details System reconstruction: integrative analysis of biological data System reconstruction: integrative analysis of biological data

2011-08-30

2011-08-30

Skowronek, Karlheinz R (Department: 1631)

Data processing: structural design, modeling, simulation, and em

Simulating nonelectrical device or system

Biological or biochemical

Reexamination Certificate

active

08010331

ABSTRACT:
The process of System Reconstruction is used to integrate sequence data, clinical data, experimental data, and literature into functional models of disease pathways. System Reconstruction models serve as informational “skeletons” for integrating various types of “high throughput” data. The present invention provides the first metabolic reconstruction study of a eukaryotic organism based solely on expressed sequence tag (EST) data.

REFERENCES:
patent: 6074616 (2000-06-01), Buechler et al.
patent: 2002/0198858 (2002-12-01), Stanley et al.
patent: 2003/0233218 (2003-12-01), Schilling
patent: WO -01/13105 (2001-02-01), None
Nakao et al. (Genome scale gene expression analysis and pathway reconstruction in KEGG, Genome Informatics, 10:94-103, 1999).
Okubo et al. (Nature Genetics, vol. 2, p. 173-179, Nov. 1992).
Karp et al. (Trends in biotechnology, vol. 17, p. 275-281, 1999).
Ochs et al. (J. Chem. Inf. Comput. Sci., vol. 36, No. 3, p. 594-601, 1996).
Ishizuka et al. (Information processing society of Japan, vol. 91, p. 73-80, Sep. 27, 2000).
Takai-Igarashi et al. (In Silico Biology, vol. 1, p. 129-146, 1999).
Forst et al. (Journal of Computational Biology vol. 6, Nos. 3/4, 1999, pp. 343-360).
Van Heyningen (Molecular Medicine, vol. 3, No. 4, Apr. 1997. 231-237).
Juty et al. (Briefings in Bioinformatics, vol. 2. No. 3, p. 223-232, Sep. 2001).
Adams et al., Curr Opin Microbiol (1998) 1(6):674-677.
Adams et al., Microbiol Mol Biol Rev (1998) 62(1):35-54.
Brakhage, Microbiol Mol Biol Rev (1998) 62(3):547-585.
Selkov et al., Gene (1997) 197:GC11-GC26.
Venter et al., Science (2001) 291:1304-1351.
Bairoch and Apweiler, Nucleic Acids Res (2000) 28:45-48.
Guzman-De-Pena et al., Antonie Van Leeuwenhoek (1998) 73(2):199-205.
Kanehisha et al., Nucleic Acids Res (2002) 30:42-46.
Karp et al., Nucleic Acids Res Res (2002) 30:56-58.
Overbeek et al., Nucleic Acids Res (2000) 28(1):123-125.
Schomburg et al., Nucleic Acids Res (2002) 30:47-49.
Selkov et al., Nucleic Acids Res (1998) 26:43-45.

Affiliated with

Also associated with

Rating

System reconstruction: integrative analysis of biological data does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with System reconstruction: integrative analysis of biological data, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and System reconstruction: integrative analysis of biological data will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2649529