System of probes enabling HLA-DR typing to be performed, and typ

Details System of probes enabling HLA-DR typing to be performed, and typ System of probes enabling HLA-DR typing to be performed, and typ

1995-06-07

1999-11-02

Campbell, Eggerton A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 231, C12Q 168, C07H 2102

Patent

active

059767898

ABSTRACT:
A set of probes for determining HLA-DR types or sub-types includes at least one of the following probes:

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B. Mach et al., "Genotypic Typing of HLA Class II: From the Bench to the Bedside", Human Immunology, vol. 30, No. 4, pp. 278-284, 1991.
Gorski et al., "Polymorphism of Human Ia antigens: gene conversion between two DR .beta. loci results in a new HLA-D/DR specificity", Nature 322:67-70, 1986.
Wordsworth et al., "HLA-DR typing using DNA amplification by the polynerase chain reaction and sequential hybridization to sequence-specific oligonucleotide probes", Immunogenetics 2:413-418, 1990.
Urdea et al., "A Comparison of Non-Radioisotopic Hybridization Assay Methods Using Fluorescent Chemiluminescent and Enzyme Labeled Synthetic Oligodeoxyribonucleotide Probes", NucliAcid Res. 16:4937-4956, 1988.
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