System, method, and computer product for exon array analysis

Details System, method, and computer product for exon array analysis System, method, and computer product for exon array analysis

2011-06-14

2011-06-14

Brusca, John S (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C700S001000, C536S024300

Reexamination Certificate

active

07962289

ABSTRACT:
In one embodiment, a method for analyzing data generated by probe arrays is described that comprises receiving user selections of two or more data files and an identification of one or more subsets of intensity values acquired from a biological probe array. The method includes iteratively opening each data file, identifying the selected subset of intensity values associated with each open data file, determining parameters for processing, storing the parameters and the identified intensity values, and closing the open data file prior to the subsequent iteration. The method then includes processing the stored intensity values using the parameters to identify one or more biological events.

REFERENCES:
patent: 2002/0147512 (2002-10-01), Bernhart et al.
Tusher et al. Significance analysis of microarrays applied to the ionizing radiation response Proc. Natl. Acad. Sci. USA vol. 98, pp. 5116-5121 (2001).
Johnson et al. Genome-Wide Survey of Human Alternative Pre-mRNA Splicing with Exon Junction Microarrays Science vol. 302 pp. 2141-2144 (2003).
Schageman et al. MarC-V: A Spreadsheet-Based Tool for Analysis, Normalization, and Visualization of Single cDNA Microarray Experiments BioTechniques vol. 32 pp. 338-340, 343, and 344 (2002).
Tseng et al. Issues in cDNA microarray analysis: quality filtering, channel normalization, models of variations and assessment of gene effects Nucleic Acids Research vol. 29, pp. 2549-2557 (2001).
Thallinger et al. Information management systems for pharmacogenomics Pharmacogenomics vol. 3, pp. 651-667 (2002).
Parrish et al. Effect of Normalization on Significance Testing for Oligonucleotide Microarrays. Journal of Biopharmaceutical Statistics vol. 14, pp. 575-589 (2004).

Affiliated with

Also associated with

Rating

System, method, and computer product for exon array analysis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with System, method, and computer product for exon array analysis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and System, method, and computer product for exon array analysis will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2700517