System for synchronous detection of fluorescence in a drop

Details System for synchronous detection of fluorescence in a drop System for synchronous detection of fluorescence in a drop

2005-06-29

2009-06-09

Porta, David P (Department: 2884)

Radiant energy

Luminophor irradiation

Methods

Reexamination Certificate

active

07544955

ABSTRACT:
A method for producing a modulated optical signal from a droplet of a liquid medium. The method positions a droplet of liquid on a hydrophobic surface, in the path of an optical beam, and modulates the shape of the droplet on this surface, by electrowetting, to modulate the signal obtained after passing the optical beam through the droplet.

REFERENCES:
patent: 4211487 (1980-07-01), Morrison et al.
patent: 6043878 (2000-03-01), Gratzl et al.
patent: 6338820 (2002-01-01), Hubbard et al.
patent: 7052244 (2006-05-01), Fouillet et al.
patent: 2002/0143437 (2002-10-01), Handique et al.
patent: 2004/0007377 (2004-01-01), Fouillet et al.
patent: 2004/0055891 (2004-03-01), Pamula et al.
patent: 2005/0048581 (2005-03-01), Chiu et al.
patent: 2 841 063 (2003-12-01), None
U.S. Appl. No. 11/630,993, filed Dec. 28, 2006, Boutet.
U.S. Appl. No. 11/916,751, filed Dec. 6, 2007, Sauter-Starace, et al.
U.S. Appl. No. 11/917,857, filed Dec. 17, 2007, Sauter-Starace, et al.
Sung Kwon Cho, et al., “Patricle Separation and Concentration Control for Digital Microfluidic Systems”, IEEE, 2003, pp. 686-689.
M. G. Pollack, et al., “Electrowetting-based actuation of droplets for integrated microfluidics”, Lab Chip, XP008038786, vol. 2, 2002, pp. 96-101 and end page.
Jean-Christophe Roulet, et al., “Performance of an Integrated Microoptical System for Fluorescence Detection in Microfluidic Systems”, Analytical Chemistry, vol. 74, No. 14, Jul. 15, 2002, pp. 3400-3407.
Hong Ren, et al., “Design and Testing of an Interpolating Mixing Architecture for Electrowetting-Based Droplet-on-Chip Chemical Dilution”, Department of Electrical and Computer Engineering, Duke University, 4 pages.
Kari T. Hjelt, et al., “High-resolution liquid volume detection in sub-nanoliter reactors”, Sensors and Actuators, vol. 83, 2000, pp. 61-66.

Affiliated with

Also associated with

Rating

System for synchronous detection of fluorescence in a drop does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with System for synchronous detection of fluorescence in a drop, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and System for synchronous detection of fluorescence in a drop will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4083762