System for regulating fluid flowing through chromatographic...

Measuring and testing – Gas analysis – Gas chromatography

Reexamination Certificate

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Reexamination Certificate

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11189467

ABSTRACT:
Disclosed are systems and methods that include a sampling device, a chromatographic column, and a transfer line through which a fluid containing analytes to be measured are communicated from the sampling device to the column. The pressure at which the fluid containing the analytes is applied at the inlet of the transfer line is adjusted as the temperature of the column increases in accordance with certain relationships in order to maintain a substantially constant flow rate or velocity for the fluid exiting the column. In this way, the system compensates for changes in the viscosity of the fluid flowing through the column that result from changes in the column temperature.

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R. Shellie, P. Marriott, P. Morrison, L. Mondello. “Effects of pressure drop on absolute retention matching in comprehensive two-dimensional gas chromatography” Journal Of Separation Science, vol. 27, No. 7-8, May 7, 2004, pp. 504-512.
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International Search Report, PCT, Oct. 17, 2005, 8 pages.

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