System for high-speed measurement and sorting of particles

Details System for high-speed measurement and sorting of particles System for high-speed measurement and sorting of particles

1996-08-23

1998-09-08

Pyon, Harold Y.

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Means for analyzing liquid or solid sample

422 68, 422 8201, 209 31, 209579, 209906, 436 8, 2504612, 364555, 356 39, G01N 3300, B07C 502

Patent

active

058041435

ABSTRACT:
A system for sorting particles is arranged such that the presence or absence of multiple parameters is determined for each particle in a flow of particles, and a logic condition is determined based on the multiple parameters. Thereafter, particles are outputted from the system when the logic condition is present. Accordingly, multiparameter high-speed measurements of a rare subpopulation of particles (e.g. biological cells) can be made amidst a larger population of particles with differing characteristics. When attached to a multiparameter flow cytometer/cell sorter and microcomputer, the system allows multiparameter analysis of cells at rates in excess of 100,000 cells/sec. This system can be an outboard module attached to a commercially available or home-built flow cytometer.

REFERENCES:
patent: 3737633 (1973-06-01), Collineau
patent: 3757213 (1973-09-01), Coulter et al.
patent: 3838549 (1974-10-01), Coulter et al.
patent: 4086631 (1978-04-01), Vick
patent: 4115806 (1978-09-01), Morton
patent: 4526276 (1985-07-01), Shoor et al.
patent: 4564598 (1986-01-01), Briggs
patent: 4653078 (1987-03-01), Aritomi et al.
patent: 4661913 (1987-04-01), Wu et al.
patent: 4727020 (1988-02-01), Recktenwald
patent: 4770992 (1988-09-01), Van den Engh et al.
patent: 4778593 (1988-10-01), Yamashita et al.
patent: 4867908 (1989-09-01), Recktenwald et al.
patent: 4882284 (1989-11-01), Kirchanski et al.
patent: 4957363 (1990-09-01), Takeda et al.
patent: 4981580 (1991-01-01), Auer
patent: 4986657 (1991-01-01), Ohe
patent: 5030002 (1991-07-01), North, Jr.
patent: 5156810 (1992-10-01), Ribi
patent: 5199576 (1993-04-01), Corio et al.
patent: 5223398 (1993-06-01), Kortright et al.
Patent Abstracts of Japan, vol. 11, No. 334 (P-631), Oct. 31, 1987, English-language Abstract of Japanese Publication No. 62-116260.
Patent Abstracts of Japan, English-language Abstract of Japanese Publication Mo. 56058676, May 21, 1981.
W.A. Bonner et al. "Fluorescein Activated Cell Sorting", Mar. 1972, Review of Scientific Instruments, vol. 43, No. 3, pp. 404-409.
D. Peters et al., The LLNL High Speed Sorter: Design Features Operational Characteristics, Biology Utility, 1985 Cytometry vol. 6 pp. 290-301.
John A. Steinkamp "Flow Cytometry", Sep. 1984, Review of Scientific Instruments, vol. 5; No. 9, pp. 1375-1400.

Affiliated with

Also associated with

Rating

System for high-speed measurement and sorting of particles does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with System for high-speed measurement and sorting of particles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and System for high-speed measurement and sorting of particles will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1279307