Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2006-08-16
2010-12-21
Carlson, Karen Cochrane (Department: 1656)
Chemistry: molecular biology and microbiology
Vector, per se
C536S023100, C530S350000
Reexamination Certificate
active
07855072
ABSTRACT:
Disclosed is a system for detecting a protease inside a cell. In one embodiment, the system includes a chimeric protein that comprises as covalently linked components: 1) at least one optionally masked signal protein; 2) at least one protease-specific cleavage site; and 3) at least one detectable amino acid sequence. The invention has a wide spectrum of applications including use in the detection of novel protease inhibitors inside cells and tissue.
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Hwang Inhwan
Kim Dae Heon
Lee Yong Jik
Ahram Biosystems Inc.
Buchanan Robert L.
Carlson Karen Cochrane
JHK Law
Kim Joseph H.
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