System for analysis of x-ray films of nucleotide sequences

Image analysis – Applications – Biomedical applications

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382181, G06K 900

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active

056664354

ABSTRACT:
A system for identification of DNA bases in a nucleotide sequence includes a microprocessor and a set of executable instructions and is configured to accept a set of input data corresponding to a DNA sequence image from an autoradiograph. In part by interpolating a distribution of density peaks derived from the set of input data, the system is configured to generate a set of output data substantially identifying or presenting the bases in the DNA sequence in a linear fashion, corresponding to the linear order of nucleotides comprising the DNA sequence. The system thereby enables identification of substantially more bases than could be read by the human eye. Enhanced electrophoresis equipment and consumables may also be applied to generate a more predictable and linear set of input data and, in turn, to generate a set of output data identifying an even greater number of DNA bases in the sequence under analysis.

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