Surgery – Radioactive substance applied to body for therapy – Radioactive substance placed within body
Reexamination Certificate
2008-03-18
2008-03-18
Lacyk, John P. (Department: 3735)
Surgery
Radioactive substance applied to body for therapy
Radioactive substance placed within body
C623S001130
Reexamination Certificate
active
11131001
ABSTRACT:
The invention provides a system which comprises a medical device that delivers a combination of therapies. These therapies include the administration of radiation, biologically active materials, cryotherapy, and thermotherapy. The present invention is also directed to a method of treating body lumen surfaces using the system of the invention. A system is provided for delivering a biologically active material to a surface of a body lumen being exposed to a radioactive source. In one aspect, the system comprises an implantable medical device which has two opposing ends, each having a surface, and a middle portion. The two opposing ends comprise a biologically active material and the middle portion of the medical device is substantially free of any biologically active material. In another aspect, the system delivers a genetic material to a surface of a body lumen which is exposed to a radioactive source. Another system is provided for treating a surface of a body lumen in which the system comprises an implantable medical device which comprises a biologically active material and a device for applying a therapy source to the parts of the body lumen surface that are in contact with the opposing ends of the medical device. The therapy source may be a cryotherapy source or a thermotherapy source.
REFERENCES:
patent: 4768507 (1988-09-01), Fischell et al.
patent: 5059166 (1991-10-01), Fischell et al.
patent: 5102402 (1992-04-01), Dror et al.
patent: 5139496 (1992-08-01), Hed
patent: 5281215 (1994-01-01), Milder
patent: 5292321 (1994-03-01), Lee
patent: 5354257 (1994-10-01), Roubin et al.
patent: 5405309 (1995-04-01), Carden, Jr.
patent: 5503614 (1996-04-01), Liprie
patent: 5789018 (1998-08-01), Engelson et al.
patent: 5840009 (1998-11-01), Fischell et al.
patent: 5843163 (1998-12-01), Wall
patent: 5863285 (1999-01-01), Coletti
patent: 5871437 (1999-02-01), Alt
patent: 5899898 (1999-05-01), Arless et al.
patent: 5902299 (1999-05-01), Jayaraman
patent: 5919126 (1999-07-01), Armini
patent: 5925353 (1999-07-01), Mosseri
patent: 5928217 (1999-07-01), Mikus et al.
patent: 5971979 (1999-10-01), Joye et al.
patent: 5997463 (1999-12-01), Cutrer
patent: 6010445 (2000-01-01), Armini et al.
patent: 6051019 (2000-04-01), Dobak, III
patent: 6074337 (2000-06-01), Tucker et al.
patent: 6096070 (2000-08-01), Ragheb et al.
patent: 6099455 (2000-08-01), Columbo et al.
patent: 6129757 (2000-10-01), Weadock
patent: 6139536 (2000-10-01), Mikus et al.
patent: 6159142 (2000-12-01), Alt
patent: 6159143 (2000-12-01), Lennox
patent: 6168619 (2001-01-01), Dinh et al.
patent: 6179789 (2001-01-01), Tu et al.
patent: 6231516 (2001-05-01), Keilman et al.
patent: 6241718 (2001-06-01), Arless et al.
patent: 6248057 (2001-06-01), Mavity et al.
patent: 6273908 (2001-08-01), Ndondo-Lay
patent: 6280411 (2001-08-01), Lennox
patent: 6299604 (2001-10-01), Ragheb et al.
patent: 6379379 (2002-04-01), Wang
patent: 6425853 (2002-07-01), Edwards
patent: 6468297 (2002-10-01), Williams et al.
patent: 6491617 (2002-12-01), Ogle et al.
patent: 6497647 (2002-12-01), Tucker
patent: 6575933 (2003-06-01), Wittenberger et al.
patent: 6656216 (2003-12-01), Hossainy et al.
patent: 6918869 (2005-07-01), Shaw et al.
patent: WO 94/26205 (1994-11-01), None
patent: WO 00/76557 (2000-12-01), None
Guha et al. Antisense ATM gene therapy: a strategy to increase the radiosensitivity of human tumors. Gene Ther. May 2000;7(10):852-858.
Gruberg et al. New concepts for radiative stents. “Conference Report: Recent Advances in Stents, Cardiovascular Radiation Therapy V and Restenosis Forum”. Feb. 5-7, 2001, Washington D.C. by Gruberg et al. Chapter title: “Stenting and Radiation”. (Http://www.medscape.com/Medscape/cardiology/2001/v05.n03/mc0606.grub/mc0606.grub-01.html).
Herrlinger et al. Transduction of human glioma cells by HSV/AAV hybrid vectors is increased by ionizing radiation. Proc. Am. Asso. for Cancer Res. Mar. 1997, 38:13 (#85).
Lojun et al. Murine intestinal crypt survival after combined taxol plus radiation exposure. Gynecol Oncol. Nov. 1996;63(2):180-183.
Spear MA. Gene therapy of gliomas: receptor and transcriptional targeting. Anticancer Res. Sep.-Oct. 1998;18(5A):3223-3231.
Steren et al. Taxol sensitizes human ovarian cancer cells to radiation. Gynecol Oncol. Feb. 1993;48(2):252-258.
Barry James
Goll Paul J.
Palasis Maria
Shaw William J.
Boston Scientific Scimed Inc.
Lacyk John P.
LandOfFree
System for administering a combination of therapies to a... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with System for administering a combination of therapies to a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and System for administering a combination of therapies to a... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3911091