Radiant energy – Invisible radiant energy responsive electric signalling – Infrared responsive
Reexamination Certificate
2011-06-07
2011-06-07
Porta, David P (Department: 2884)
Radiant energy
Invisible radiant energy responsive electric signalling
Infrared responsive
Reexamination Certificate
active
07956328
ABSTRACT:
An ATR-FTIR device and system are described that defect live-cell responses to stimuli and perturbations in real-time. The system and device can monitor perturbations resulting from exposures to various physical, chemical, and biological materials in real-time, as well as those sustained over a long period of time, including those associated with stimuli having unknown modes-of-action (e.g. nanoparticles). The device and system can also be used to identify specific chemical species or substances that profile cellular responses to these perturbations.
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Communication Relating to the Results of the Partial International Search.
Miyamoto, K., et al., In situ observation of a cell adhesion and megabolism using surface infrared spectroscopy, Cytotechnology, Kluwer Academic Publishers, DO, DOI 10.1007/S10616-007-9111-2, vol. 55, No. 2-3, Nov. 27, 2007, pp. 143-149.
Hutson, T. B., et al, A Technique for Monitoring Mammalian Cell Growth and Inhibition in Situ via Fourier Transform Infrared Spectroscopy, Analytical Biochemistry, Academic Press, Inc., New York, DOI 10.1016/003-2697(88)90040-1, vol. 174, No. 2, Nov. 1, 1988, pp. 415-422.
Shankaran, D. R., et al., Recent advancements in surface plasmon resonance immunosensors for detection of small molecules of biomedical, food and environmental interest, Sensors and Actuators B, Elsevier Sequoia S.A., Lausanne, DOI: 10.1016/J.SNB.2006.09.014, vol. 121, No. 1, Jan. 23, 2007, pp. 158-177.
Ojeda, J. J., et al., In situ monitoring of the biofilm formation ofPseudomonas putidaon hematite using flow-cell ATR-FTIR spectroscopy to investigate the formation of inner-sphere bonds between the bacteria and the mineral, Mineralogical Magazine, 2008 Mineralogical Society GB, vol. 72, No. 1, 2008, pp. 101-106.
Taylor, A. D., et al., Quantitative and simultaneous detection of four foodborne bacterial p;athogens with a multi-channel SPR sensor, Biosensors and Bioelectronics, Elsevier BV, DOI: 10.1016/J.BIOS.2006.03.012, vol. 22, No. 5, Dec. 15, 2005, pp. 752-768.
Miyamoto, K., et al., In situ observation of a cell adhesion and megabolism using surface infrared spectroscopy, Cytotechnology, Kluwer Academic Publishers, DO, DOI 10.1007/S10616-007-9111-2, vol. 55, No. 2-3, Nov. 27, 2007, pp. 143-149.
Hutson, T. B., et al, A Technique for Monitoring Mammalian Cell Growth and Inhibition in Situ via Fourier Transform Infrared Spectroscopy, Analytical Biochemistry, Academic Press, Inc., New York, DOI 10.1016/003-2697(88)90040-1, vol. 174, No. 2, Nov. 1, 1988, pp. 415-422.
Shankaran, D. R., et al., Recent advancements in surface plasmon resonance immunosensors for detection of small molecules of biomedical, food and environmental interest, Sensors and Actuators B, Elsevier Sequoia S.A., Lausanne, DOI: 10.1016/J.SNB.2006.09.014, vol. 121, No. 1, Jan. 23, 2007, pp. 158-177.
Ojeda, J. J., et al., In situ monitoring of the biofilm formation ofPseudomonas putidaon hematite using flow-cell ATR-FTIR spectroscopy to investigate the formation of inner-sphere bonds between the bacteria and the mineral, Mineralogical Magazine, 2008 Mineralogical Society GB, vol. 72, No. 1, 2008, pp. 101-106.
Taylor, A. D., et al., Quantitative and simultaneous detection of four foodborne bacterial p;athogens with a multi-channel SPR sensor, Biosensors and Bioelectronics, Elsevier BV, DOI: 10.1016/J.BIOS.2006.03.012, vol. 22, No. 5, Dec. 15, 2005, pp. 752-768.
International Search Report/Written Opinion for International Application No. PCT/US2010/034940, International Filing Date May 14, 2010, Date of Mailing Jan. 7, 2011.
Addleman R. Shane
Riley Brian J.
Sacksteder Colette A.
Sundaram S. Kamakshi
Weber Thomas J.
Battelle (Memorial Institute)
Gaworecki Mark R
Matheson James D.
Porta David P
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