Surgery – Diagnostic testing – Measuring or detecting nonradioactive constituent of body...
Reexamination Certificate
2005-06-28
2005-06-28
Dahbour, Fadi H. (Department: 3743)
Surgery
Diagnostic testing
Measuring or detecting nonradioactive constituent of body...
C600S473000, C600S476000, C600S477000, C600S478000, C600S407000, C356S342000
Reexamination Certificate
active
06912412
ABSTRACT:
The present invention utilizes a plurality of spectroscopic systems and methods to measure characteristics of tissue useful in the diagnosis of disease. In a preferred embodiment, a combination of fluorescence, reflectance and light scattered spectra can be measured and processed to provide biochemical, architectural and morphological state of tissue. The methods and systems can be used particularly in the early detection of carcinoma within tissue in vivo and in vitro.
REFERENCES:
patent: 4768513 (1988-09-01), Suzuki
patent: 4773097 (1988-09-01), Suzaki et al.
patent: 5201318 (1993-04-01), Rava et al.
patent: 5280788 (1994-01-01), Janes et al.
patent: 5304173 (1994-04-01), Kittrell et al.
patent: 5318024 (1994-06-01), Kittrell et al.
patent: 5345941 (1994-09-01), Rava et al.
patent: 5419323 (1995-05-01), Kittrell et al.
patent: 5421337 (1995-06-01), Richards-Kortum et al.
patent: 5452723 (1995-09-01), Wu et al.
patent: 5562100 (1996-10-01), Kittrell et al.
patent: 5582168 (1996-12-01), Samuels et al.
patent: 5697373 (1997-12-01), Richards-Kortum et al.
patent: 6008889 (1999-12-01), Zeng et al.
patent: 6091984 (2000-07-01), Perelman et al.
patent: 6321111 (2001-11-01), Perelman et al.
patent: 6404497 (2002-06-01), Backman et al.
patent: 2002/0093563 (2002-07-01), Cline et al.
patent: 0 449 883 (1991-10-01), None
patent: 2002-95624 (2002-04-01), None
patent: WO 99/18845 (1999-04-01), None
patent: WO 00/42912 (2000-07-01), None
patent: WO 01/34031 (2001-05-01), None
Richards-Kortum, R. et al, “A One-Layer Model of Laser-Induced Fluorescence for Diagnosis of Disease in Human Tissue: Applications to Atherosclerosis,” IEEE Transactions on Biomedical Engineering, vol. 36, No. 12, Dec. 1989, pp. 1221-1232.
Yang, C., et al., “Feasibility of field-based light scattering spectroscopy,”Journal of Biomedical Optics5(2):138-143 (Apr. 2000).
Perelman, L.T., et al., “Observation of Periodic Fine Structure in Reflectance from Biological Tissue: A New Technique for Measuring Nuclear Size Distribution,”Physical Review Letters80(3):627-630 (1998).
Backman, V., et al., “Detection of Preinvasive Cancer Cells,”Nature406:35-36 (2000).
Zonios, G., et al., “Diffuse Reflectance Spectroscopy of Human Adenomatous Colon Polyps In Vivo,”Applied Optics38(31): 6628-6637 (1999).
Panjehour, M., et al., “Endoscopic Fluorescence Detection of High-Grade Dysplasia In Barrett's Esophagus,”Gastroenterology111:93-101 (1996).
Wallace, M.B., et al., “Endoscopic Detection of Dysplasia In Patients with Barrett's Esophagus Using Light-Scattering Spectroscopy,”Gastroenterology119:667-682 (2000).
Zhang, Q., et al., “Turbidity-Free Fluorescence Spectroscopy of Biological Tissue,”Optics Letters25(19):1451-1453 (2000).
Georgakoudi, I., et al., “Fluorescence, Reflectance and Light Scattering Spectroscopy for Evaluating Dysplasia in Patients with Barrett's Esophagus,”Gastroenterology, pp. 1-15, downloaded Dec. 6, 2000 from http://www.gastro-central.org/view.
Yang, C. et al., “Phase Dispersion Optical Tomography,”Optics Letterspp. 1-12 (Abstract) (2000).
“Tri-Modal Spectroscopy—A New Approach to Spectroscopic Detection of Cervical Neoplasia in Vivo,” (abstract).
Georgakoudi, I., “Spectroscopy for Detection of Cancer,” Presented at the APS Mar. 2001 Meeting in Seattle Washington.
Feld Michael S.
Georgakoudi Irene
Mueller Markus G.
Zhang Qingguo
Dahbour Fadi H.
Massachusetts Institute of Technology
Weingarten Schurgin, Gagnebin & Lebovici LLP
LandOfFree
System and methods of fluorescence, reflectance and light... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with System and methods of fluorescence, reflectance and light..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and System and methods of fluorescence, reflectance and light... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3512516