System and methods for harvesting mononuclear cells by recircula

Details System and methods for harvesting mononuclear cells by recircula System and methods for harvesting mononuclear cells by recircula

1997-07-01

1999-11-09

Kim, John

Liquid purification or separation

Processes

Separating

210 85, 210 86, 210 97, 210143, 210194, 2101951, 210739, 210745, 210789, 210805, 494 1, 494 2, 494 37, 604410, B01D 2126

Patent

active

059807601

ABSTRACT:
A blood separation system operates in a first mode to convey whole blood into the inlet region of a blood processing chamber for centrifugal separation into packed red blood cells, a plasma constituent, and an interface, which carries mononuclear cells, between the packed red blood cells and the plasma constituent. The system removes packed red blood cells and the plasma constituent from the chamber, while maintaining the interface within the chamber. The system operates in a second mode to remove the interface from the chamber by conveying packed red blood cells into the inlet region. An outlet path conveys the removed interface from the chamber. The outlet path includes a first sensing element to locate mononuclear cells in the removed interface and provide a sensed output upon locating mononuclear cells.

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