System and method of measuring methylation of nucleic acids

Details System and method of measuring methylation of nucleic acids System and method of measuring methylation of nucleic acids

2011-03-01

2011-03-01

Zeman, Mary K (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C702S020000, C703S011000, C703S012000, C703S013000, C707S700000, C435S006120, C435S007100

Reexamination Certificate

active

07899626

ABSTRACT:
The present embodiments relate to a system and method of measuring the methylation level of DNA. Some embodiments relate to a system and method of measuring methylation level of DNA with a gene array.

REFERENCES:
patent: 6713258 (2004-03-01), Kilian
patent: 7153671 (2006-12-01), Berlin
patent: 2004/0002818 (2004-01-01), Kulp et al.
patent: 2005/0164246 (2005-07-01), Fan et al.
Kuss et al. LC-GC Europe, Dec. 2003, pp. 1-4.
Smith, Ian M, et al. “DNA Global Hypomethylation in Squamous Cell Head and Neck Cancer Associated with Smoking, Alcohol Consumption and Stage.” International Journal of Cancer. 121.8 (2007): 1724-1728.
Ushijima Toshikzau, et al. “Decreased Fidelity In Replicating CpG Methylation Patterns in Cancer Cells.” Cancer Research. 65.1 (2005): 11-17.
Zhao, Xinxin, et al. “Epigenetic Inheritance and Variation of DNA Methylation Level and Pattern In Maize Intra-Specific Hybrids.” Plant Science. 172 (2007): 930-938.
BeadStudio Methylation Module User Guide: A Modular Tool for Illumina Data Analysis. Illumina Proprietary, 2006.
Illumina BeadStudio Data Analysis Software Module. Illumina Inc, 2006.
Bibikova, Marina, et al. “High-Throughput DNA Methylation Profiling Using Universal Bead Arrays.” Genome Research. 16 (2006): 383-393. Dec. 6, 2006 <http://www.genome.org>.
“Media Release: Biotage Expands Pyrosequencing® Performance in Quantitative DNA Methylation Analysis for Clinical Cancer Research.” Jul. 27, 2009. <http://www.pyrosequencing.com/Print.aspx?id=32517>.
Yang, Allen S., et al.“A Simple Method For Estimating Global DNA Methylation Using Bisulfite PCR of Repetitive DNA Elements”. Nucleic Acids Research. 32.3 (2004): 1-6.
Wirtz, Michaela, et al. “Determination of the DNA Methylation Level in Tumor Cells by Capillary Electrophoresis and Laser-Induced Fluorescence Detection.” Electrophoresis. 25 (2004): 839-845.
Tost, Jorg, et al. “Analysis and Accurate Quantification of CpG Methylation by MALDI Mass Spectrometry.” Nucleic Acids Research. 31.9 (2003): 1-10.
“Pyro Q-CpG™: Quantitative Analysis of Methylation in Multiple CpG sites by Pyrosequencing.” Nature Methods. (2005): i-ii.
Weisenberger, Daniel J. “Analysis of repetitive element DNA methylation of MethyLight.” Nucleic Acids Research. 33.21 (2005): 1-10.

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