System and method of illuminating living cells for imaging

Details System and method of illuminating living cells for imaging System and method of illuminating living cells for imaging

2006-11-28

2006-11-28

Allen, Stephone B. (Department: 2878)

Radiant energy

Luminophor irradiation

C250S459100, C356S317000, C356S318000, C356S417000

Reexamination Certificate

active

07141801

ABSTRACT:
A system and method of providing illumination for a cell imaging system delivering modulated light for illumination of a sample. Modulation of illumination intensity may be effectuated by pulsing the output of a light source, for example, or by selectively interrupting light provided by the source. Such modulated illumination may have particular utility in applications where reducing the number of electrons in a super-excited state may minimize the rate of photobleaching and photodamage in the molecules being studied.

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patent: 6614031 (2003-09-01), Engelhardt et al.
patent: 6953927 (2005-10-01), Quake et al.

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