Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation
Patent
1997-02-28
1999-07-06
Lateef, Marvin M.
Surgery
Diagnostic testing
Detecting nuclear, electromagnetic, or ultrasonic radiation
604 4, 604 52, 600419, 600420, 600408, 378 4, A61B 600
Patent
active
059191350
ABSTRACT:
A system and method is provided for the treatment of hypreproliferative diseases, such as cancer, using real-time computer control to visualize, to position and to operate drug infusing and imaging devices within the body of the patient. The invention employs a computerized imaging system (such as CAT scan, MRI imaging, ultrasound imaging, infrared, X-ray, UV/visible light fluorescence, Raman spectroscopy, single photon emission computed tomography or microwave imaging) to sense the position of a drug infusing catheter within the body. In a preferred embodiment, the invention provides real-time computer control to maintain and adjust the position of an infusion catheter and/or the position of the patient relative to the infusion catheter; and also provides real-time computer control of the operation of the infusion catheter based on images and/or computer models of the dispersion of one or more cytotoxic or other drugs or therapeutically active agents through the vascular bed of the neoplastic tissue being treated. In other preferred embodiments of the invention, vasoconstrictive drugs are applied locally based on computer modeling of blood flow patterns in order to channel blood flow carrying the cytotoxic drug or other therapeutic agent into the neoplastic tissue, and to minimize exposure of healthy tissue to such drugs.
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Lateef Marvin M.
Shaw Shawna J.
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