System and method for tracking and controlling infections

Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical

Reexamination Certificate

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C702S020000, C703S011000, C707S700000, C536S024100

Reexamination Certificate

active

08046172

ABSTRACT:
The present invention is a system and method for performing real-time infection control over a computer network. The method comprises obtaining a sample of a microorganism at a health care facility, sequencing a first region of a nucleic acid from the microorganism sample, comparing the first sequenced region with historical sequence data stored in a database, determining a measure of phylogenetic relatedness between the microorganism sample and historical samples stored in the database, and providing infection control information based on the phylogenetic relatedness determination to the health care facility, thereby allowing the health care facility to use the infection control information to control or prevent the spread of an infection.

REFERENCES:
patent: 5396227 (1995-03-01), Carroll et al.
patent: 5619991 (1997-04-01), Sloane
patent: 5660981 (1997-08-01), Grosz et al.
patent: 5691136 (1997-11-01), Lupski et al.
patent: 6404340 (2002-06-01), Paradiso et al.
patent: WO 98/50555 (1998-11-01), None
patent: WO 99/51771 (1999-10-01), None
patent: WO 01/70955 (2001-09-01), None
patent: WO 02/20827 (2002-03-01), None
A. van Belkum et al. “Are Variable Repeats in the spa Gene Suitable Targets for Epidemiological Studies of Methicillin-Resistant Staphylococcus aureus Strains?,” 15 European J. Clin. Microbiol. Infect. Dis., Letters 768-770 (1996).
A. van Belkum et al., “Outbreak of Amoxicillin-ResistantHaemophilus influenzaType b: Variable Numer of Tandem Repeats as Novel Molecular Markers,” 35(6) Journal of Clinical Microbiology 1517-1520 (1997).
A. van Belkum et al., “Short-Sequence DNA Repeats in Prokaryotic Genomes,” 62(2) Microbiology and Molecular Biology Reviews 275-293 (1998).
A. van Belkum, “Short sequence repeats in microbial pathogenesis and evolution,” 56(9-10) Cell. Mol. Life Sci. 729-734 (Nov. 1999).
A. van Belkum, “The role of short sequence repeats in epidemiologic typing,” 2(3) Current Opinion in Microbiol. 306-311 (Jun. 1999).
A. van Belkum et al., “Variable Number of Tandem Repeats in Clinical Strains ofHaemophilus influenza,” 65(12) Infection and Immunity 5017-5027 (1997).
Benson et al., 25 Nucleic Acids Research 1-6 (1997).
Philippe Castagnone-Sereno et al., “Unusual and Strongly Structured Sequence Variation in a Complex Satellite DNA Family from the NematodeMeloidogyne chitwoodi,” 46 J Mol Evol 225-233 (1998).
CDC Plan: “Preventing Emerging Infectious Diseases: a strategy for the 21st Century,” 1-68 (Atlanta, Georgia, Oct. 1998).
Database EMBL Online AAS53198, Feb. 13, 2002.
Database EMBL Online AAX13101Enterococcus faecalis genome contig SEQ IDNo. 164, Mar. 19, 1999.
Database EMBL Online AEO16947, Mar. 29, 2003.
R. Durbin et al., “Biological Sequence Analysis,” Probablistic Models of Proteins and Nucleic Acids 17-19 (Press Syndicate of The University of Cambridge, 1998).
M. Enright et al., “Multilocus Sequence Typing,” 7(12) Trends in Microbiol. 482-487 (Dec. 1999).
I. T. Paulsen et al. “Role of Mobile DNA in the Evolution of Vancomycin-Resistant Enterococcus faecalis,” 299(5615) Science 2071-2074 (Mar. 28, 2003).
H.M.E. Frenay et al., “Molecular Typing of Methicillin-Resistant Staphylococcus aureus on the Basis of Protein A Gene Polymorphism,”. 15(1) European J. Clin. Microbiol. Infect. Dis. 60-64 (1996).
Richard Frothingham, “Differentiation of Strains inMycobacterium tuberculosisComplex by DNA Sequence Polymorphisims, including Rapid Identification ofM. bovisBCB,” Journal of Clinical Micrbiology 840-844 (Apr. 1995).
Richard Frothingham et al., “Genetic diversity in theMycobacterium tuberculosiscomplex based on variable numbers of tandem DNA repeats,” 144 Microbiology 1189-1196 (1998).
Stephen V. Gordon et al., “New insertion sequences and a novel repeated sequence in the genome of Mycobacterium tuberculosisH37Rv,” 145 Microbiology 881-892 (1999).
M. Goyal et al., “Rapid detection of multidrug-resistant tuberculosis,” 10 European Respiratory J 1120-1124 (1997).
Griffiths et al., “An Introduction to Genetic Analysis,” W.H. Freeman & Co. 1-3 (1999).
Greiser-Wilke et al., “Structure and Presentation of a World Wide Web Database of CSF Virus Isolates Held at the EU Reference Laboratory,” 73 Vet. Microbio. 131-136 (2000).
Dan Gusfield, “Algorithms on Strings, Trees, and Sequences,” 215-219 (Press Syndicate of the University of Cambridge, 1999).
Hoe et al., “Rapid Molecular Genetic Subtyping of Serotype M1 Group A Streptococus Strains,” 5(2) Emerg. Infect. Dis. 254-263 (1999).
Nancy P. Hoe et al., “Rapid selection of complement-inhibiting protein variants in group A Streptococcus epidemic waves,” 5(8) Nature Medicine 924-929 (Aug. 1999).
N. Kobayashi et al., “Analysis of genomic diversity within the Xr-region of the protein A gene in clinical isolates of Staphylococcus aureus,” 122 Epidemiol. Infect. 241-249 (1999).
Herminia de Lencastre et al., “Testing the Efficacy of a Molecular Surveillance Network: Methicillian-Resistant Staphylococcus aureus(MRSA)and Vancomycin-Resistant Enterococcus faecium(VREF)Genotypes in Six Hospitals in the Metropolitan New York City Area,” 2(3) Microbial Drug Resistance 344-351 (1996).
Levitt, “The US-EU Conference on Extension of the Salm/Enter-net Surveillance Systems for Human Salmonella and Escherichia coli O157 Infections,” 4(3) Emerg. Infect. Dis. 502-503 (1998).
Martin C.J. Maiden et al., “Multilocus sequence typing: A portable approach to the identification of clones within populations of pathogenic microorganisms,” 95 Proc. Natl. Acad. Sci. 3140-3145 (Mar. 1998).
O'Brien et al., “DNA Fingerprints FromMycobacterium tuberculosisIsolates of Patients Confined for Therapy Noncompliance Show Frequent Clustering,” 112(2) Chest 387-392 (1997).
Richet et al., “Building Communication Networks: International Network for the Study and Prevention of Emerging Antimicrobial Resistance,” 7(2) Emerging Infect. Dis. 319-322 (Mar.-Apr. 2001).
Robert J. Rubin et al., “The Economic Impact ofStaphylococcus aureusInfection in New York City Hospitals,”, 5(1) Emerging Infectious Diseases 9-17 (Jan.-Feb. 1999).
David Sankoff et al., “Time Warps, Sting Edits, and Macromolecules, the Theory and practice of Sequence Comparison,” CSLI Publications 1999, Chapter 2, Recognition of Patterns in Genetic Sequences, B. Ericksson et al., pp. 55-57.
B. Shopsin et al., “Evaluation of Protein A Gene Polymorphic Region DNA Sequencing for Typing of Staphylococcus aureus Strains,” 37(11) J. Clin. Micr. 3556-3563 (1999).
B. Shopsin et al., “Use of Coagulase Gene(coa)Repeat Region Nucleotide Sequences for Typing of Methicillin-Resistant Staphylococcus aureus Strains,” 38(9) J. Clin. Microbial. 3453-3456 (Sep. 2000).
Brian Spratt, “Multilocus Sequence Typing: Molecular Typing of Bacterial Pathogens in an Era of Rapid DNA Sequencing and the Internet,” 2 Microbiology 312-316 (1999).
Kathryn E. Stockbauer et al., “Hypervariability generated by natural selection in an extracellular complement-inhibiting protein of serotype M1 strains of groupA. Streptococcus,” 95 Proc. Natl. Acad. Sci USA 3128-3133 (Mar. 1998).
Website, pp. 1-8: http//cpsweb.cps.ca/English/statements/ID/id99-03.htm, Infectious Diseases and Immunization committee, Canadian Paediatric Society (CPS), “Control of methicillin resistantStaphylococcus aureusin Canadian paediatric institutions is still a worthwhile goal,” (Jun. 12, 2000).

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