Chemistry: analytical and immunological testing – Involving diffusion or migration of antigen or antibody
Reexamination Certificate
2003-02-26
2010-02-02
Lam, Ann Y (Department: 1641)
Chemistry: analytical and immunological testing
Involving diffusion or migration of antigen or antibody
Reexamination Certificate
active
07655477
ABSTRACT:
A separation module operates to fractionate or separate an analyte into fractions according to pI, i.e., pI bands, utilizing capillary isoelectric focusing (“CIEF”) within a first microchannel. The fractions are stacked to form plugs, the number of which is determined by a number of parallel second microchannels integrally connected to the first microchannel, into which the fractions are directed according to the buffer characteristics found in each of the individual microchannels. Within the microchannels the plugs are separated into proteins according to a different chemical property, i.e., “m/z,” utilizing capillary electrophoresis (“CE”).
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Baraniuk James N.
Schneider Thomas Wayne
Georgetown University
King & Spalding LLP
Lam Ann Y
Science Applications International Corporation
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