System and method for testing neural stimulation threshold

Details System and method for testing neural stimulation threshold System and method for testing neural stimulation threshold

2011-02-09

2011-10-18

Manuel, George (Department: 3762)

Surgery: light, thermal, and electrical application

Light, thermal, and electrical application

Electrical therapeutic systems

Reexamination Certificate

active

08041423

ABSTRACT:
Various system embodiments comprise a neural stimulator, a premature ventricular contraction (PVC) event detector, a heart rate detector, an analyzer, and a controller. The neural stimulator is adapted to generate a stimulation signal adapted to stimulate an autonomic neural target. The analyzer is adapted to, in response to a PVC event signal from the PVC event detector, generate an autonomic balance indicator (ABI) as a function of pre-PVC heart rate data and post-PVC heart rate data. Other aspects and embodiments are provided herein.

REFERENCES:
patent: 5603331 (1997-02-01), Heemels et al.
patent: 6026320 (2000-02-01), Carlson et al.
patent: 6301499 (2001-10-01), Carlson et al.
patent: 6529772 (2003-03-01), Carlson et al.
patent: 6678547 (2004-01-01), Carlson et al.
patent: 6718197 (2004-04-01), Carlson et al.
patent: 6748272 (2004-06-01), Carlson et al.
patent: 7062314 (2006-06-01), Zhu et al.
patent: 7079887 (2006-07-01), Burnes et al.
patent: 2003/0040774 (2003-02-01), Terry et al.
patent: 2003/0199937 (2003-10-01), Carlson
patent: 2004/0158295 (2004-08-01), Dyjach et al.
patent: 2004/0186525 (2004-09-01), Burnes et al.
patent: 2004/0193066 (2004-09-01), Carlson et al.
patent: 2004/0210261 (2004-10-01), King et al.
patent: 2004/0230241 (2004-11-01), Carlson et al.
patent: 2005/0090719 (2005-04-01), Scheiner et al.
patent: 2005/0149132 (2005-07-01), Libbus
patent: 2005/0234353 (2005-10-01), Xue et al.
patent: 2005/0261741 (2005-11-01), Libbus et al.
patent: 2006/0106428 (2006-05-01), Libbus et al.
patent: 2006/0106429 (2006-05-01), Libbus et al.
patent: 2006/0135998 (2006-06-01), Libbus et al.
patent: 2007/0276453 (2007-11-01), Hill et al.
patent: 2008/0086182 (2008-04-01), Ben-David et al.
“U.S. Appl. No. 12/861,370, Notice of Allowance mailed Oct. 12, 2010”, 12 pgs.
Adamopoulos, S., “Effects of pulsed beta-stimulant therapy on beta-adrenoceptors and chronotropic responsiveness in chronic heart failure.”, Lancet, 345(8946), (Feb. 11, 1995), 344-9.
Bauer, A., et al., “Turbulence dynamics: an independent predictor of late mortality after acute myocardial infarction.”, Int J Cardiol., 107(1), (2006), 42-7.
Coats, A. J., “Controlled trial of physical training in chronic heart failure. Exercise performance, hemodynamics, ventilation, and autonomic function.”, Circulation, 85(6), (Jun. 1992), 2119-31.
Iwasa, A., et al., “Abnormal heart rate turbulence predicts the initiation of ventricular arrhythmias.”, Pacing Clin Electrophysiol., 28(11), (2005), 1189-97.
Leier, C. V., “Drug-induced conditioning in congestive heart failure.”, Circulation, 65(7), (Jun. 1982), 1382-7.
Liang, C., “Conditioning effects of chronic infusions of dobutamine. Comparison with exercise training.”, Journal of Clinical Investigation, 64(2), (Aug. 1979), 613-9.
Malberg, H., et al., “Short-term Heart Rate Turbulence Analysis Versus Variability and Baroreceptor Sensitivity in Patients With Dilated Cardiomyopathy.”, Indian Pacing Electrophysiol J., 4(4), (2004), 162-75.
Moore, R. K., et al., “Heart rate turbulence and death due to cardiac decompensation in patients with chronic heart failure.”, Eur J Heart Fail., 8(6), (2006), 585-90.
Schwab, J. O., et al., “Influence of basic heart rate and sex on heart rate turbulence in healthy subjects.”, Pacing Clin Electrophysiol., 27(12), (2004), 1625-1631.
Wichterle, D., et al., “Hemodynamics and autonomic control of heart rate turbulence.”, J Cardiovasc Electrophysiol., 17(3), (2006), 286-91.
Wichterle, D., et al., “Turbulence slope after atrial premature complexes is an independent predictor of mortality in survivors of acute myocardial infarction.”, J Cardiovasc Electrophysiol., 15(12), (2004), 1350-6.

Affiliated with

Also associated with

Rating

System and method for testing neural stimulation threshold does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with System and method for testing neural stimulation threshold, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and System and method for testing neural stimulation threshold will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4280792