Data processing: structural design – modeling – simulation – and em – Simulating nonelectrical device or system – Biological or biochemical
Reexamination Certificate
2007-12-04
2007-12-04
Moran, Marjorie A (Department: 1631)
Data processing: structural design, modeling, simulation, and em
Simulating nonelectrical device or system
Biological or biochemical
C702S019000
Reexamination Certificate
active
10360796
ABSTRACT:
The present invention relates to a system and method for examining pathways. In particular, the present invention provides a system and method for examining pathways that underlie cellular functions, specifically signal transduction pathways. One aspect of the invention relates to the prediction of (a) functional properties of a protein, (b) potential interaction partners of the protein, and/or (c) potential target biochemical pathways within which the protein may interact. Thus, according to the invention, the influence of a given stimulus on a biochemical pathway can be assessed.
REFERENCES:
patent: 4518866 (1985-05-01), Clymer
patent: 4736322 (1988-04-01), Clifford
patent: 5136687 (1992-08-01), Edelman et al.
patent: 5273038 (1993-12-01), Beavin
patent: 5526281 (1996-06-01), Chapman et al.
patent: 5553004 (1996-09-01), Gronbech-Jensen et al.
patent: 5621671 (1997-04-01), Bodnar
patent: 5657255 (1997-08-01), Fink et al.
patent: 5680331 (1997-10-01), Blaney et al.
patent: 5680590 (1997-10-01), Parti
patent: 5699268 (1997-12-01), Schmidt
patent: 5751928 (1998-05-01), Bakalash
patent: 5808918 (1998-09-01), Fink et al.
patent: 5914891 (1999-06-01), McAdams et al.
patent: 5930154 (1999-07-01), Thalhammer-Reyero
patent: 5963212 (1999-10-01), Bakalash
patent: 5980096 (1999-11-01), Thalhammer-Reyero
patent: 6051029 (2000-04-01), Paterson et al.
Scott et al., Cell Communication: The Inside Story, Scientific American, vol. 282 No. 6, pp. 72-79 Jun. 2000.
Karp, P.D., Computer Comer: Metabolic databases, TIBS, vol. 23, pp. 114-116 (Mar. 1998).
Clancey, W.J., From Guidon to Neomycin and Heracles in Twenty Short Lessons: ORN Final Report 1979-1985, The Al Magazine, Aug. 1986, pp. 40-60.
Bourne, J.R., Critical Reviews In Biomedical Engineering, 19(4): 261-292 (1992), pp. 261-292.
Karp et al., EcoCyc: Encyclopedia ofEscherichia coliGenes and Metabolism; Nucleic Acids Research, 1997, vol. 25, No. 1, pp. 43-50.
Karp, P.D., Bioinformatics: Database links are a foundation for interoperability, TIBTECH, Aug. 1996 (vol. 14), pp. 273-279.
Paley, et al., Gene-Combis: Adapting EcoCyc for use on the World Wide Web, Gene 172 (1996) GC43-GC50.
Karp, P.D., Journal Of Computational Biology, A Strategy for Database Interoperation, vol. 2, No. 4, 1995, pp. 573-586.
Karp, P.D., Representation of Metabolic Pathways, ISMB-94, pp. 204-211, 1994.
Karp et al., The EcoCyc and MetaCyc databases, Nucleic Acids Research 2000, vol. 28, No. 1, pp. 56-59.
Karp, P.D., Hypothesis Formation and Qualitative Reasoning in Molecular Biology, Al Magazine, pp. 9-11 (Winter 1990).
Ouzounis et al., Resource: Global Properties of the Metabolic Map ofEscherichia coli, Genome Research, 10: 568-576, 2000.
Karp et al., Representations of Metabolic Knowledge, ISMB-93, pp. 207-215, 1993.
Karp et al., HinCyc: A Knowledge Base of the Complete Genome and Metabolic Pathways ofH. influenzae, ISMB-96, pp. 116-124, 1996.
Karp et al., Focus: Integrated pathway-genome database and their role in drug discovery, TIBTECH, Jul. 1999 (vol. 17), pp. 275-281.
The WWW Virtual Library of Cell Biology: Signal Transduction, pp. 1-3, printed from http://vl.bwh.harvard.edu/signal—transduction.shtml, Jun. 15, 2000.
Cell Signaling Networks Database, pp. 1-2, [retrieved on Jun. 15, 2000] Retrieved from <http://geo.nihs.go.jp/cgi-bin/display—tissue/MAP-kinase>.
Kohn, K.W., “Functional capabilities of molecular network components controlling the mammalian GI/S cell cycle phase transition”, Oncogene (1998), vol. 16, pp. 1065-1075.
Abouhamad, et al., “Computer-Aided Resolution of an Experimental Paradox in Bacterial Chemotaxis”, Journal Of Bacteriology, Aug. 1998, vol. 180, No. 15, pp. 3757-3764.
PCT International Preliminary Examination Report, PCT/US01/07794, mailed Sep. 4, 2003.
Ogata et al., “KEGG: Kyoto Encyclopedia of Genes and Genomes”,Nuc. Acids Res. (Jan. 1999), vol. 27, No. 1, pp. 29-34.
Allen Eric B.
Allen Sandra
Armstrong John
Fragoso Gilberto
Blackwell Sanders LLP
Milligan David H.
Moran Marjorie A
New World Science & Technology, Inc.
LandOfFree
System and method for simulating cellular biochemical pathways does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with System and method for simulating cellular biochemical pathways, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and System and method for simulating cellular biochemical pathways will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3860157