System and method for screening for dementia

Optics: eye examining – vision testing and correcting – Eye examining or testing instrument – Objective type

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351246, A61B 310

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active

059561254

ABSTRACT:
An easily administered, non-invasive, sensitive and specific system and method for screening persons for dementia, particularly dementia of the Alzheimer's type, is provided. The system and method include means for irradiating the eye of a person with light, preferably light solely within the infrared spectrum, and means for generating a signal responsive to the amount of light reflected from the eye over a period of time. This signal is indicative of changes in the pupil's size over time. The system and method further include means for performing a Fourier transform upon this signal to provide a value indicative of the strength of this signal's frequency components. This value then is compared against a predetermined threshold value and, if this threshold value is exceeded, a higher probability is assigned to the person having dementia, particularly dementia of the Alzheimer's type.

REFERENCES:
patent: 4755043 (1988-07-01), Carter
patent: 4850691 (1989-07-01), Gardner et al.
patent: 5187506 (1993-02-01), Carter
patent: 5297562 (1994-03-01), Potter
patent: 5311879 (1994-05-01), Yamada et al.
patent: 5345944 (1994-09-01), Hongo et al.
patent: 5490098 (1996-02-01), Kardon
patent: 5535760 (1996-07-01), Potter
patent: 5557113 (1996-09-01), Moorhouse et al.
patent: 5595883 (1997-01-01), Appleyard et al.
patent: 5617872 (1997-04-01), Scinto et al.
patent: 5627612 (1997-05-01), Hayashi
patent: 5646709 (1997-07-01), Carter
patent: 5661538 (1997-08-01), Carter
patent: 5692502 (1997-12-01), Alpert
patent: 5704369 (1998-01-01), Scinto et al.
Rosse et al., A Measure of Pupillary Oscillation as a Marker of Cocaine-Induced Paranoia, Journal of Neuropsychiatry, vol. 8, No. 3, pp. 347-350 (1996).
Thomas D. Bird, Apolipoprotein E Genotyping in the Diagnosis of Alzheimer's Disease: A Cautionary View, Annals of Neurology, vol. 38, No. 1, pp. 2-3 (1995).
Grunberger et al., Pupillometry in Clinical Psychophysiological Diagnostics: Methodology and Proposals for Application in Psychiatry, Isr J. Psychiatry Relat Sci, vol. 29, No. 2, pp. 100-113 (1992).
Bouma et al., Hippus of the Pupil: Periods of Slow Oscillations of Unknown Origin, Vision Res. vol. 11, pp. 1345-1351 (1971).
Salmon et al., Longitudinal Evaluation of Dementia of the Alzheimer Type: A Comparison of 3 Standardized Mental Status Examinations, Neurology, vol. 40, pp. 1225-1230 (1990).
Currie et al., Eye Movement Abnormalities as a Predictor of the Acquired Immunodeficiency Syndrome Dementia Complex, Arch Neurol, vol. 45, pp. 949-953 (1988).
Fletcher et al., Saccadic Eye Movement Dysfunction in Alzheimer's Disease, Annals of Neurology, vol. 20, No. 4, pp. 464-470 (1986).
Richard E. Gans, The Eye Clinic Frequently Asked Questions--Alzheimer's Disease, http://ofcn.org/cyber.serv/hwp/hwc/eye/information/faq/alzheimer.html (1994).
American Association for Clinical Chemistry, Eye-Drop Test Unreliable for Diagnosing Alzheimer's, http://aacc.org/cln/profiles/97profiles/01/diagpro9706.html (1996).
Ivanhoe Broadcast News, Inc., Ivanhoe's Medical Breakthroughs--Alzheimer's Eye Test Q&A #962, http://www.ivanhoe.com/docs/backissues/alzheimerseyetestqa.html (1997).
P/S/L Consulting Group Inc., Mayo Jacksonville Study Shows Eye Test Fails as Alzheimer's Diagnosis, http://www.pslgroup.com/dg/2a96a.htm (1997).
Merrill et al., Ocular Motor Abnormalities in Human Immunodeficiency Virus Infection, Annals of Neurology, vol. 30, No. 2, pp. 130-138 (1991).
Applied Science Group, Inc., ASL-About Eye Tracking and Pupillometry, http://world.std.com/.about.asl/aboutet.html (1997).

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