Chemistry: electrical and wave energy – Processes and products – Electrostatic field or electrical discharge
Patent
1991-10-04
1992-05-26
Niebling, John
Chemistry: electrical and wave energy
Processes and products
Electrostatic field or electrical discharge
204299R, G01N 2726, B01D 5702
Patent
active
051164710
ABSTRACT:
The method for improving sample concentration in capillary electrophoresis by extracting the sample buffer from the capillary column using the electro-osmotic flow while the sample components are stacked into the support buffer utilizes a system for this technique. The system has a separation column 11, sample introduction means 16 for injecting the sample solution, an injection detector means 20 for detecting the volume of injected sample solution, a separation detector means 21 for detecting the sample components, power supply means 17 for applying a high voltage along the separation column 11 for reversing the direction of the electro-osmotic flow thereby causing extraction of the sample buffer from the separation column and afterward providing the separation sample into its components.
REFERENCES:
Ruedi Aebersold & Hamish D. Morrison "Analysis of dilute peptide samples by capillary zone electrophoresis" Journal of Chromatography 516 (1990) 79-88.
Henk H. Lauer et al. "Analytical Aspects of an Automated Capillary Electrophoresis System" LC-GC vol. 6, No. 1 (1990) 34-46.
F. E. B. Mikkers, F. M. Everaerts, & Th. P. E. M. Verheggen "High-Performance Zone Electrophoresis" Journal of Chromatography 169 (1979) 11-20.
Dean S. Burgi & Ring-Ling Chien "Optimization in Sample Stacking for High-Performance Capillary Electrophoresis" Analytical Chemistry, vol. 63, No. 18 (1991) 2042-2047.
Moring, Stephen E., "Analytical Aspects of an Automated Capillary Electrophoresis System," LC-GC, vol. 8, No. 1 (1990) 34-46.
Jorgenson, James W. et al. "Capillary Zone Electrophoresis", Science, vol. 222, (1983), pp. 266-272.
Nielen, M. W. F., "Impact of Experimental Parameters on the Resolution of Positional Isomers of Aminobenzoic Acid in Capillary Zone Electrophoresis," Journal of Chromatography, 542 (1991) 173-183.
Burgi Dean S.
Chien Ring-Ling
Niebling John
Starsiak Jr. John S.
Varian Associates Inc.
LandOfFree
System and method for improving sample concentration in capillar does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with System and method for improving sample concentration in capillar, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and System and method for improving sample concentration in capillar will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-417243