Surgery – Endoscope – Having endotrachael intuabation means on endoscope
Reexamination Certificate
2006-08-22
2006-08-22
Wehbe′, Anne M. (Department: 1633)
Surgery
Endoscope
Having endotrachael intuabation means on endoscope
C600S119000, C600S122000, C600S009000, C514S04400A, C435S320100
Reexamination Certificate
active
07094201
ABSTRACT:
The present invention provides delivery systems for and methods of delivering conduction protein genetic material to cardiac cells in localized areas of the heart to improve the conductance therein. More specifically, there is provided a system and method for delivering connexin proteins or nucleic acid molecules encoding connexin proteins to a site in the heart which has been determined by mapping procedures to have a conduction disturbance. For cases where conduction is impaired, selected genetic material is delivered to cells around the disturbance area, in order to enhance overall conductivity patterns; in other cases, genetic material is selected to slow conduction in affected areas, so as to prevent, e.g., brady-tachy syndrome.
REFERENCES:
patent: 4360031 (1982-11-01), White
patent: 4699147 (1987-10-01), Chilson
patent: 4711251 (1987-12-01), Stokes
patent: 5019034 (1991-05-01), Weaver et al.
patent: 5030204 (1991-07-01), Badger
patent: 5041107 (1991-08-01), Heil
patent: 5060660 (1991-10-01), Gambale
patent: 5176641 (1993-01-01), Idriss
patent: 5297549 (1994-03-01), Beatty
patent: 5397339 (1995-03-01), Desai
patent: 5443450 (1995-08-01), Kratoska
patent: 5797870 (1998-08-01), March
patent: 6567705 (2003-05-01), Stokes et al.
patent: 6665563 (2003-12-01), Stokes et al.
patent: WO 93/04724 (1993-03-01), None
patent: WO 94/11506 (1994-05-01), None
patent: WO 94/11506 (1995-03-01), None
patent: WO 95/05781 (1995-03-01), None
Kanter et al, J. Mol. Cell. Cardiol. 26: 861-868, 1994.
E. Marshall, Gene therapy growing pains; 1995 Science, vol. 269:1050-1055.
Orkin et. al., Report and recommendations of the panel to assess the NIH investment in research on gene therapy, 1995.
Alexander, M.Y. et al, Clin Exp Pharmacol Physiol 1999, Sep. 26 (9) 661-668.
Maurice, J.P., et al, J. Clin. Invest. Jul. 1999; 104(1) pp. 21-29.
Ascadi, et al.,The New Biol., 1991, 3, 71-81.
Barr, et al.,Gene Ther., 1994, 1, 51-58.
Chomczynsky, et al.,Anal. Biochem., 1987, 162, 156-159.
Davis, et al.,J. Am. Coll. Cardiol., 1994, 24, 1124-1132.
Fishman, et al.,J. Cell Biol., 1990, 111, 589-598.
French, et al.,Circulation, 1994, 90, 2414-2424.
Gal, et al.,Lab. Invest., 1993, 68, 18-25.
Gluzman, et al., inEukaryotic Viral Vectors, Gluzman, ed., Cold Spring Harbor Press, 1982, pp. 187-192.
Gourdie, et al.,J. Cell Sci., 1993, 105, 985-991.
Kanter, et al.,J. Mol. Cell Cardiol., 1994, 26, 861-868.
Kriegler, M. “Gene Transfer and Expression, a Laboratory Manual”, W.H. Freeman Co., New York (1990).
Murry, E.J. e.d. “Methods in Molecular Biology”, vol. 7, Humana Press, Inc., Cliffton, New Jersey (1991).
Parmacek, et al.,J. Biol. Chem., 1990, 265, 15970-15976.
Parmacek, et al.,Mol. Cell Biol., 1992, 12, 1967-1976.
Saffitz, et al.,J. Card. Electrophys., 1995, 6, 498-510.
Sambrook et al.,Molecular Cloning: A Laboratory Manual, Second Ed. Cold Spring Harbor Press (1989), pp. 7.26-7.29.
Sambrook et al.,Molecular Cloning: A Laboratory Manual, Second Ed. Cold Spring Harbor Press (1989), pp. 16.1-16.55.
Morissette Josée
Stokes Kenneth B.
Collier Ken
Jaro Michael
Medtronic Inc.
Wehbe′ Anne M.
Woods Thomas F.
LandOfFree
System and method for genetically treating cardiac... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with System and method for genetically treating cardiac..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and System and method for genetically treating cardiac... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3693229