Optics: measuring and testing – By dispersed light spectroscopy – With raman type light scattering
Reexamination Certificate
2007-03-05
2008-12-30
Evans, F. L (Department: 2877)
Optics: measuring and testing
By dispersed light spectroscopy
With raman type light scattering
C356S328000
Reexamination Certificate
active
07471389
ABSTRACT:
The present disclosure describes methods and systems that combine Raman spectroscopy performed in a manner that utilizes one or more of widefield illumination, simultaneous multipoint Raman spectral acquisition, and spectral unmixing for the purpose of high throughput polymorph screening. Features of this methodology include: (a) high throughput polymorph screening to reduce crystal orientation effects on Raman spectra; (b) in-well multi-polymorph screening using increased statistical sampling; and (c) multipoint spectral sampling to enable spectral unmixing.
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Nelson Matthew P.
Treado Patrick J.
Tuschel David
ChemImage Corporation
Evans F. L
Morris LLP Duane
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