System and method for estimating cardiac output

Surgery – Truss – Pad

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128713, A61B 5029

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active

056877331

ABSTRACT:
Cardiac output CO is separately estimated in a local estimator and a trend estimator to provide CO values. A thermal signal is injected preferably according to a pseudo-random binary sequence signal profile at an upstream position in a blood flow region of a patient's body and is sensed as an indicator output signal at a downstream position. Low-frequency noise is preferably removed from the sensed indicator output signal. The local and trend estimations are based on measured frequency-domain transfer function values between the sensed and input indicator signal in relation to a pre-determined transfer function model, which is preferably a lagged normal model. The trend estimator is preferably a Kalman filter. The local estimator preferably forms its estimate based on non-recursive optimization of a cost function. The local estimator preferably provides initial values to start the trend estimator.

REFERENCES:
patent: 4238527 (1980-12-01), Newbower et al.
patent: 4507974 (1985-04-01), Yelderman
patent: 5146414 (1992-09-01), McKown et al.
patent: 5357967 (1994-10-01), Dixon et al.
patent: 5363856 (1994-11-01), Hughes et al.
Yelderman, M., J. Clinical Monitoring vol. 6 (Oct. 1990), pp. 322-332, "Continuous Measurement of Cardiac Output with the Use of Stochastic Identification Techniques".

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