Electrolysis: processes – compositions used therein – and methods – Electrolytic analysis or testing – Of biological material
Reexamination Certificate
2004-04-16
2010-10-26
Michener, Jennifer K (Department: 1795)
Electrolysis: processes, compositions used therein, and methods
Electrolytic analysis or testing
Of biological material
C435S006120, C435S287200, C204S403010
Reexamination Certificate
active
07820030
ABSTRACT:
The present invention relates to an electrochemical method for detecting a target polynucleotide. An electrode comprising an electrode surface is provided. The electrode surface includes at least one probe molecule reversibly immobilized with respect to the electrode surface. A first electrochemical signal indicative of an amount of probe molecule immobilized with respect to the electrode surface is obtained. The electrode surface is contacted with a liquid comprising the target polynucleotide. Upon the contacting step, at least some of the probe molecule immobilized with respect to the electrode surface dissociates therefrom. A second electrochemical signal indicative of an amount of probe molecule immobilized with respect to the electrode surface is obtained. The presence of the target polynucleotide is determined at least partially on the basis of the first and second electrochemical signals.
REFERENCES:
patent: 5312527 (1994-05-01), Mikkelsen et al.
patent: 5869244 (1999-02-01), Martin et al.
patent: 5968745 (1999-10-01), Thorp et al.
patent: 6132580 (2000-10-01), Mathies et al.
patent: 6740518 (2004-05-01), Duong et al.
patent: 2002/0155477 (2002-10-01), Ito
Gooding (Electrochemical DNA Hybridization Biosensors, Electroanalysis, vol. 14, issue 17, pp. 1149-1156, 2002).
Wang (Nanoparticle-based electrochemical DNA detection, Analytica Chimica Acta 500 (2003) 247-257).
Alvarez et al., New Scheme for electrochemical detection of DNA based on electocatalytic oxidation of NADH, Electrochemistry Communications, 5, 2003, pp. 267-271.
Mascini et al., DNA electrochemical biosensors, J. Anal. Chem., 2001, 369, pp. 15-22.
Dequaire, et al., “Screen Printing of Nucleic Acid Detecting Carbon Electrodes”, Anal. Chem., 74:4370-4377, (2002).
Cho, et al., “Fabrication of a Multi-Electrode Array DNA Sensor for Electrochemical Genotyping”, Journal of the Korean Physical Society, 41(6):1054-1057, (Dec. 2002).
de-los-Santos Alvarez, et al., “New Scheme for Electrochemical Detection of DNA Based on Electrocatalytic Oxidation of NADH”, Electrochemistry Communications, 5:267-271, (2003).
Piedade, et al., “Electrochemical Sensing of DNA-Adriamycin Interactions”, Bioelectrochemistry, 56:81-83, (2002).
Plambeck, et al., “Electrochemical Studies of Antitumor Antibiotics”, J. Electrochem Soc.: Electrochemical Science and Technology, pp. 2556-2563, (Dec. 1984).
Wang, “Survey and Summary, from DNA Biosensors to Gene Chips”, Nucleic Acids Research, 28(16):3011-3016, (2000).
Zhang, et al., “Carbon Paste Electrode Based on Surface Activation for Trace Adriamycin Determination by a Preconcentration and Voltammetric Method”—Analytical Sciences, 18:1089-1092, (Oct. 2002).
Boon, “Electrochemical Sensors Based on DNA-Mediated Charge Transport Chemistry”, Thesis submitted to Calif. Inst. of Tech., Pasadena, CA, Chap. II: 27-55, (Aug. 2002).
Popovich, “Mediated Electrochemical Detection of Nucleic Acids Discovery and Clinical Diagnosis”, Med. Devicelink archive, pp. 1-8 (Apr. 1, 2003).
Mascini, et al., “DNA Electrochemical Biosensors”, Fresenius J. Anal. Chem. 369:15-22, (2001).
Althaus John S.
Brahmasandra Sundaresh N.
Handique Kalyan
Kyonghoon Lee
Namasivayam Vijay
Dieterle Jennifer
HandyLab, Inc.
Knobbe Martens Olson & Bear LLP
Michener Jennifer K
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