System and method for dynamic chemical imaging

Optics: measuring and testing – By dispersed light spectroscopy – With raman type light scattering

Reexamination Certificate

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Reexamination Certificate

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07317526

ABSTRACT:
A system and method for detecting dynamic changes that occur in a sample between a first time interval and a second time interval using a series of at least first and second sequential chemical images of the sample. During the first time interval: (i) the sample is illuminated with a plurality of photons to thereby produce photons scattered or emitted by the sample; (ii) a two-dimensional array of detection elements is used to simultaneously detect scattered or emitted photons in a first predetermined wavelength band from different locations on or within the sample; and (iii) the two-dimensional array of detection elements is thereafter used one or more further times to simultaneously detect scattered or emitted photons in one or more further predetermined wavelength band(s) from different locations on or within the sample. The outputs of the two-dimensional array of detection elements during the first time interval are then combined to generate the first chemical image of the sample. The process is repeated during the second time interval to generate the second chemical image of the sample. Dynamic changes occurring in the sample between the first time interval and the second time interval are detected based on one or more differences between the first and second chemical images.

REFERENCES:
patent: 5377003 (1994-12-01), Lewis et al.
patent: 5528393 (1996-06-01), Sharp et al.
patent: 5626134 (1997-05-01), Zuckerman
patent: 5784162 (1998-07-01), Cabib et al.
patent: 5866430 (1999-02-01), Grow
patent: 5910816 (1999-06-01), Fontenot et al.
patent: 6002476 (1999-12-01), Treado
patent: 6052187 (2000-04-01), Krishnan et al.
patent: 6069690 (2000-05-01), Xu et al.
patent: 6175750 (2001-01-01), Cook et al.
patent: 6181414 (2001-01-01), Raz et al.
patent: 6274871 (2001-08-01), Dukor et al.
patent: 6300618 (2001-10-01), Tanaami et al.
patent: 6483641 (2002-11-01), MacAulay
patent: 6485413 (2002-11-01), Boppart et al.
patent: 6640130 (2003-10-01), Freeman et al.
patent: 6640132 (2003-10-01), Freeman et al.
patent: 6697665 (2004-02-01), Rava et al.
patent: 6741884 (2004-05-01), Freeman et al.
patent: 6810279 (2004-10-01), Mansfield et al.
patent: 6937885 (2005-08-01), Lewis et al.
patent: 6939686 (2005-09-01), Ling et al.
patent: PCT/CA98/00092 (1998-08-01), None
Treado et al., “Indium Antimonide (InSb) Focal Plane Array(FPA) Detection for Near-Infrared Imaging Microscopy,” Applied Spectroscopy 48 (1994) p. 607.
Morris, Hoyt, Miller and Treado, “Liquid Crystal Tunable Filter Raman Chemical Imaging,” Applied Spectroscopy, No. 50, No. 6, (Jun. 1996) pp. 805-811.
Patrick J. Treado, “Chemical Imaging Reveals More Than The Microscope,” Laser Focus World, (Oct. 1995) pp. 1-7.
Morris, “Utrasensitive Raman and Flourescence Imaging Using Liquid Crystal Tunable Filters,” SPIE vol. 2385, (1995) pp. 81-87.
Treado et al., “Infrared Raman Spectroscopic Imaging,” (Marcell Decker, 1992) pp. 71-108.
Treado et al., “High-Fidelity Raman Imaging Spectrometry: A Raid Method Using an Acousto-Optic Tunable Filter”, Applied Spectroscopy, vol. 46, No. 8 (1992) pp. 1211-1216.
Treado et al., “Near-Infrared Acousto-Optic Filtered Spectoscopic Microscopy: A Solid-State Approach to Chemical Imaging,” Applied Spectroscopy, vol. 46, No. 4 (1992) pp. 553-559.
Morris et al., “Imaging Spectometers for Fluorescence and Raman Microscopy: Acousto-Optic and Liquid Crystal Tunable Filter,” Applied Spectroscopy, vol. 48, No. 7, (1994) pp. 857-860.
Turner et al., “LCTF Raman Chemical Imaging in the Near-Infrared,” SPIE vol. 3061 (1997) pp. 280-283.
Miller et al., “Multispectral Imaging with a Liquid Crystal Tunable Filter,” SPIE vol. 2345, (1995) pp. 354-365.
Ling et al., “Direct Raman Imaging Techniques for Study of the Subcellular Distribution of a Drug,” Applied Optics, vol. 41, No. 28, (2002) pp. 6000-6017.

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