System and method for detecting solid components of ground...

Image analysis – Applications – Biomedical applications

Reexamination Certificate

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C378S021000

Reexamination Certificate

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07747052

ABSTRACT:
A method for detecting solid components in ground glass nodules (GGNs) in medical images, includes: performing an intensity-based segmentation on a segmented GGN to identify a high intensity region; and performing a shape analysis to determine whether the high intensity region is a solid component or a vessel, wherein the shape analysis comprises: computing a compactness of the high intensity region; and determining whether the high intensity region is a solid component or a vessel by using an area, a maximum distance on a distance transform map and the compactness of the region; or determining whether the high intensity region is a solid component or a vessel by scaling and normalizing the region and computing a compactness for the scaled and normalized region.

REFERENCES:
patent: 6937776 (2005-08-01), Li et al.
patent: 2005/0254697 (2005-11-01), Zhang et al.
patent: 2006/0120585 (2006-06-01), Zhang et al.
Feng Li, MD, PhD, et al., “Malignant versus Benign Nodules at CT Screening for Lung Cancer: Comparison of Thin-Section CT Findings,” Radiology (2004) 233:793-798.
Zhang Li, et al., “A Computer-based Method of Segmenting Ground Glass Nodules in Pulmonary CT Images: Comparison to Expert Radiologists' Interpretations,” In Proc. SPIE Medical Imaging, Image Processing (j. Michael Fitzpatrick and Joseph M. Reinhardt, eds.) vol. 5747 pp. 113-121 (2005).

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