Chemistry: analytical and immunological testing – Optical result
Reexamination Certificate
2004-11-18
2008-11-04
Chin, Christopher L (Department: 1641)
Chemistry: analytical and immunological testing
Optical result
C356S244000, C356S246000, C356S436000, C356S440000, C356S521000, C422S082050, C422S082110, C435S287200, C435S288700, C436S165000, C436S524000, C436S527000, C436S805000
Reexamination Certificate
active
07445938
ABSTRACT:
The present invention is directed to an optical grating sensor configured to detect a phase change in light passing though the system due to a binding event caused by an analyte. The grating sensor may include a light source that may be, for example, a coherent light source. The invention may also include a first diffraction grating having a first period. A micro-electrical mechanical system (MEMS) may be displaced from the first diffraction grating and may be configured to modulate the light received form the coherent light source. An analyte recognition material may be disposed on the surface of the first grating. A detector may be configured to receive light form the coherent light source after the light has been diffracted from the first diffraction grating and modulated by the MEMS. In another embodiment of the present invention, the grating sensor may be configured to operate in two modes. The first mode may be a mode the detect a phase change in the light due to a binding event. The second mode may include the detection of fluorescence due to a binding event and may employ tagging of the analytes.
REFERENCES:
patent: 4487839 (1984-12-01), Kamentsky
patent: 4517456 (1985-05-01), Halsall et al.
patent: 4876208 (1989-10-01), Gustafson et al.
patent: RE33581 (1991-04-01), Nicoli et al.
patent: 5071248 (1991-12-01), Tiefenthaler et al.
patent: 5081012 (1992-01-01), Flanagan et al.
patent: 5082629 (1992-01-01), Burgess, Jr. et al.
patent: 5196350 (1993-03-01), Backman et al.
patent: 5413939 (1995-05-01), Gustafson et al.
patent: 5442169 (1995-08-01), Kunz
patent: 5559601 (1996-09-01), Gallatin et al.
patent: 5577137 (1996-11-01), Groger et al.
patent: 5578833 (1996-11-01), Ohmi et al.
patent: 5679579 (1997-10-01), Gustafson
patent: 5846843 (1998-12-01), Simon
patent: 5922550 (1999-07-01), Everhart et al.
patent: 5959292 (1999-09-01), Duveneck et al.
patent: 5999319 (1999-12-01), Castracane
patent: 6060256 (2000-05-01), Everhart et al.
patent: 6061166 (2000-05-01), Furlani et al.
patent: 6180288 (2001-01-01), Everhart et al.
patent: 6221579 (2001-04-01), Everhart et al.
patent: 6312961 (2001-11-01), Voirin et al.
patent: 6326144 (2001-12-01), Bawendi et al.
patent: 6333507 (2001-12-01), Lai et al.
patent: 6573040 (2003-06-01), Everhart et al.
patent: 6579673 (2003-06-01), McGrath et al.
Chin Christopher L
General Dynamics Advanced Information Systems Inc.
Steptoe & Johnson
LandOfFree
System and method for detecting presence of analytes using... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with System and method for detecting presence of analytes using..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and System and method for detecting presence of analytes using... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4028363