Radiant energy – Luminophor irradiation – Methods
Reexamination Certificate
2007-01-25
2008-07-22
Hannaher, Constantine (Department: 2884)
Radiant energy
Luminophor irradiation
Methods
C250S458100
Reexamination Certificate
active
07402817
ABSTRACT:
The present invention is directed to a system and method for cross-talk cancellation for multi-lane fluorescence detectors. The invention may be implemented in accordance with a variety of systems, including systems for multi-capillary electrophoresis. The present invention is based on a special calibration procedure for determination of a channel cross-talk matrix and enables an accurate separation of the fluorescence emitted from individual capillary lanes. The proposed method for cross-talk calibration and removal is very useful for design and development of multi-lane single photon counting detection systems.
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Gavrilov et al., “Dynamic Range Of Fluorescence Detection And Base-Calling Accuracy In DNA Sequencer Based On Single-Photon Counting,” Electrophoresis 2003, 24, 1184-1192.
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Gavrilov Dmitri N.
Gorbovitski Boris
Gorfinkel Vera
Gudkov Georgiy
Tcherevishnik Marina
Hannaher Constantine
The Research Foundation of State University of New York
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