Synthetic yeast leader peptides

Details Synthetic yeast leader peptides Synthetic yeast leader peptides

1989-09-12

1992-11-10

Lacey, David L.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

435 699, C07K 710

Patent

active

051624982

ABSTRACT:
Synthetic yeast leader peptides are disclosed which aid in extracellular secretion of heterologous proteins made recombinantly in yeast.

REFERENCES:
patent: 4546082 (1985-10-01), Kurjan
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Egel-Mitani et al., Nucleic Acids Research, vol. 15, No. 15, pp. 6303-6304 (1987).
Egel-Mitani et al., Gene, vol. 73, pp. 113-120 (1988).
Kaiser et al., Science, vol. 235, pp. 312-317 (1987).
Andrews et al., J. Biol. Chem., vol. 263, No. 30, pp. 15791-15798 (1988).
Duffaud et al., J. Biol. Chem., vol. 263, No. 21, pp. 10224-10228 (1988).

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