Synthetic virus-like particles with heterologous epitopes

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S345000, C424S204100, C424S205100, C424S178100

Reexamination Certificate

active

07033797

ABSTRACT:
The invention is a series of synthetic virus-like particles comprising a heterologous conformational epitope useful in the characterization of human papillomavirus infection, and useful to vaccinate individual for protection against HPV 6 and HPV 11 infections, and assays employing the synthetic virus-like particles.

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patent: 5985610 (1999-11-01), Lowy et al.
patent: 6013262 (2000-01-01), Frazer et al.
patent: WO 97/04076 (1997-02-01), None
patent: WO 97 18301 (1997-05-01), None
Jenison et al . Journal of Virology, 1989, vol. 63, No. 2, pp. 809-818.
Ludmerer, et al; Journal of Virology, vol. 70, No. 7, pp 4791-4794, 1996.
Ludmerer, et al; Journal of Virology, vol. 71, pp 3834-39, 1997.
Christensen, et al; Virology, 224(2): 477-486, 1996.

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