Synthetic vaccine peptide epitomes of hepatitis B surface antige

Details Synthetic vaccine peptide epitomes of hepatitis B surface antige Synthetic vaccine peptide epitomes of hepatitis B surface antige

1980-01-14

1983-11-15

Fagelson, Anna P.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424 86, 424 89, 424177, 436820, A61K 3702, A61K 3929, C07C10352, C07G 700

Patent

active

044154917

ABSTRACT:
Novel oligopeptides are provided having serologic activity for the a determinant of hepatitis B virus surface antigen. Included in the oligopeptide chain are a sequence of at least two cysteines and a lysine in proximity to the cysteines. The oligopeptides can find use in immunoassays, the formulation of vaccines, and the production of antisera.

REFERENCES:
Charnay et al., Nucleic Acid Res., vol. 7, 1979, p. 355.
Valenzuela et al., Nature, vol. 280, 1979, p. 815.
Rao, Microbios, vol. 10, 1974, pp. 233-238.
Vyas et al. (Ed.) Viral Hepatitis, Sym. 2nd. U. of Calif., Mar. 1978, The Franklin Inst. Press, Philadelphia, 1978, pp. 121-138, 147-153, 557-573, 645-648, 712, 713.

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