Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1977-04-06
1978-08-29
Phillips, Delbert R.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424177, C07C10352
Patent
active
041103211
ABSTRACT:
A tridecapeptide, [Gln.sup.4 ]-neurotensin, has been effectively synthesized and which has the sequence (pyro)glutamyl-leucyl-tyrosyl-glutaminyl-asparaginyl-lysyl-prolyl-arginyl- arginyl-prolyl-tyrosinyl-isoleucyl-leucyl-acid. [Gln.sup.4 ]-neurotensin has the unique hormonal activities and chemical structure of the native hormone in bovine hypothalamic tissue.
REFERENCES:
R. Carraway et al., The Journal of Biological Chemistry 250, 1975, pp. 1907-1918
R. Carraway et al., The Journal of Biological Chemistry 248, 1973, pp. 6854-6861.
Mitri Salvatore C.
Phillips Delbert R.
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