Synthetic senescent cell antigen

Details Synthetic senescent cell antigen Synthetic senescent cell antigen

1990-05-24

1992-10-20

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530326, C07K 708, A61K 3702

Patent

active

051570203

ABSTRACT:
Disclosed herein is a synthetic senescent cell antigen comprised of purified peptides immunoreactive with antibodies to the naturally occurring antigen. Preferably, the synthetic senescent cell antigen comprises two peptides with the amino acid sequences SKLIKIFQDHPLQKTYN and LFKPPKYHPDVPYVKR, respectively. The antigen and peptides may be used in compositions, diagnostic kits, and methods for detecting or measuring antibodies to senescent cell antigen, studying cellular aging and autoimmune mechanisms, separating anions from a gas or liquid, or treating certain diseases.

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Kay, et al. Proc. natl. Acad. Sci. U.S.A., 83:2463-2467 (1986).
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