Synthetic resin matrix drug storage and topical drug delivery dr

Details Synthetic resin matrix drug storage and topical drug delivery dr Synthetic resin matrix drug storage and topical drug delivery dr

1985-11-27

1988-02-16

Phillips, Delbert R.

Surgery

Means and methods for collecting body fluids or waste material

Absorbent pad for external or internal application and...

128156, 128334R, 523111, 514936, 514946, 514965, 524104, 524111, 524167, 524173, 524233, 524296, 524317, 524560, C08K 541, C08K 534, C08K 515, C08K 510

Patent

active

047252715

ABSTRACT:
A synthetic resin matrix dressing is disclosed consisting essentially of a polymer, such as poly(2-hydroxyethylmethacrylate), referred to as PHEMA, an organic solvent, such as polyethylene glycol (PEG), and a hydrogen bonding plasticizer, such as dimethylsulfoxide (DMSO). The plasticizer regulates the set-up time of the synthetic resin so that the more plasticizer present, the shorter the set-up time. The dressing may be applied to the treatment site in veterninary use in the form of a paste for the in-situ curing or setting thereof, or the dressing may be preformed and then applied to the treatment site. A variety of drug agents may be incorporated in the synthetic resin matrix so as to result in the time released administration of the drug agent to the area of the skin covered by the dressing. A method of treatment using this dressing is also disclosed.

REFERENCES:
patent: 3551554 (1970-12-01), Herschler
patent: 3575946 (1971-04-01), Chromacek et al.
patent: 3577516 (1971-05-01), Gould et al.
patent: 4243656 (1981-01-01), Walliczek
patent: 4272518 (1981-06-01), Moro et al.
patent: 4294820 (1981-10-01), Keith et al.

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