Synthetic proteolytic substrate

Details Synthetic proteolytic substrate Synthetic proteolytic substrate

1990-03-13

1993-06-15

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548161, 435800, 435 23, 435 24, 436800, C07D27718, C07D27782, C07D27760, C72Q 138

Patent

active

052200299

ABSTRACT:
A reagent for proteolytic enzyme assays has the general formula ##STR1## where RCO-- is an enzyme reactive acyl, such as an amino acid, peptide or substituted amino acid or peptide. The reagent may by hydrolyzed by proteolytic enzymes and developed to form a distinctive color. The reagent may be formed by reacting RCOOH with N-hydroxysuccinimide to form the acyl N-hydroxysuccinimide ester. The ester may then be reacted to form the reagent.

REFERENCES:
patent: 4950593 (1990-08-01), Matta et al.

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