Synthetic polypeptides and receptor molecules derived therefrom

Details Synthetic polypeptides and receptor molecules derived therefrom Synthetic polypeptides and receptor molecules derived therefrom

1987-08-21

1989-12-26

Rosen, Sam

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

436512, 436518, 436528, 436536, 436540, 436543, G01N 3353, G01N 33563

Patent

active

048898007

ABSTRACT:
Antigens, immunogens, inocula, antibodies, receptors, diagnostic methods and systems relating to tuberculosis mycobacteria are disclosed. Each of the compounds, compositions, methods or systems contains about 40 residues, or an antibody containing site that immunoreacts with such a polypeptide. The polypeptide includes the thirteen or fourteen amino acid reside sequence (AlaLysValAsnIleLysProLeuGluAspLysIleCys) or (CysAlaLysValAsnIleLysproLeuGluAspLysIleCys). When linked to a carrier and introduced in an effective amount into a mammalian host, the polypeptide is capable of inducing production of antibodies that immunoreact with an antigen to a tuberculous mycobacterium.

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