Synthetic polypeptides and antibodies related to epstein-barr vi

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 15 to 23 amino acid residues in defined sequence

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530324, 530325, 530229, H11K 3800, H11K 3804, C12N 500, C12N 700

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active

057170657

ABSTRACT:
Antigens, immunogens, inocula, antibodies, and particularly diagnostic methods and systems relating to Epstein-Barr virus nuclear antigen (EBNA) are disclosed. The diagnostic methods and systems utilize a synthetic, random copolymer polypeptide containing about 6 to about 40 amino acid residues having a sequence corresponding to the sequence of a CMV-encoded polypeptide antigen. The diagnostic methods and systems are particularly useful in identifying infections mononucleosis during its acute phase.

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patent: 5116725 (1992-05-01), Vaughn et al.
Dillner et al. 1984. Antibodies against a synthetic peptide identify the Epstein-Barr . . . PNAS. 81:4652-4656.
Rhodes et al. 1985. Human Immune Responses to Synthetic peptides from . . . J. Immunol. 134(1):211-216.
Jahn et al. 1984. Predominant Immediate Early . . . J. Virol. 49(2):363-70.
Staprans et al. 1986. 2.2.-Kilobase Class of Early . . . J. Virol. 57(2):591-602.
Luka et al. 1984. Identification and Characterization . . . J. Virol. 52(3):833-38.

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