Synthetic polypeptide with laminin activity

Details Synthetic polypeptide with laminin activity Synthetic polypeptide with laminin activity

1989-05-08

1992-06-09

Lee, Lester L.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

15 to 23 amino acid residues in defined sequence

514 13, A61K 3702, C07K 708

Patent

active

051208288

ABSTRACT:
A polypeptide having the following formula is provided: arg-ile-gln-asn-leu-leu-lys-ile-thr-asn-leu-arg-ile-lys-phe-val-lys; which can bind heparin and promote cellular adhesion.
Medical devices such as prosthetic implants, percutaneous devices and cell culture substrates coated with a composition including the polypeptide are also provided.

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