Synthetic polypeptide fragments

Details Synthetic polypeptide fragments Synthetic polypeptide fragments

1983-06-10

1985-06-04

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424 88, C07C10352, A61K 3900, A61K 3700

Patent

active

045213348

ABSTRACT:
Peptide fragments of streptococcal M protein named CB3, CB4, and CB5 and related synthetic peptides have been identified. When linked to a protein carrier which is polylysine the conjugates of CB3, CB4, CB5, and S-CB3 are capable of evoking type specific opsonic antibodies against streptococci.

REFERENCES:
patent: 4284537 (1981-08-01), Beachey
Nature, 232, (311), 1971, pp. 478-480.
The Journal of Biological Chemistry, 258, (1983), 13250-13257.
Nature, 292, (1981), 457-459.
Infection & Immunity, (1984), pp. 122-126, vol. 43, No. 1.
Federation Proceedings, vol. 42, (7), 1983, p. 309.
Biol. Abstr., vol. 50, 20361, (1936).
Biochem. & Biophys. Res. Commun., 92, No. 2, (1980), 546-553.

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